product summary
company name :
Dako
product type :
antibody
product name :
Glial Fibrillary Acidic Protein (GFAP)
catalog :
M0761
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6F2
reactivity :
human, mouse, rat, dogs, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 44
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 2a
Fares M, Cochet Bernoin M, Gonzalez G, Montero Menei C, Blanchet O, Benchoua A, et al. Pathological modeling of TBEV infection reveals differential innate immune responses in human neurons and astrocytes that correlate with their susceptibility to infection. J Neuroinflammation. 2020;17:76 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1b
Mitrofanova L, Hazratov A, Galkovsky B, Gorshkov A, Bobkov D, Gulyaev D, et al. Morphological and immunophenotypic characterization of perivascular interstitial cells in human glioma: Telocytes, pericytes, and mixed immunophenotypes. Oncotarget. 2020;11:322-346 pubmed publisher
  • immunohistochemistry - frozen section; rat; loading ...; fig s1a
N diaye M, Brauner S, Flytzani S, Kular L, Warnecke A, Adzemovic M, et al. C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation. J Clin Invest. 2020;130:838-852 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100; loading ...; fig 11d
Mammone T, Chidlow G, Casson R, Wood J. Improved immunohistochemical detection of phosphorylated mitogen-activated protein kinases in the injured rat optic nerve head. Histochem Cell Biol. 2019;151:435-456 pubmed publisher
  • immunohistochemistry; domestic rabbit; 1:2400; loading ...; fig 2d
Phakdeedindan P, Setthawong P, Tiptanavattana N, Rungarunlert S, Ingrungruanglert P, Israsena N, et al. Rabbit induced pluripotent stem cells retain capability of in vitro cardiac differentiation. Exp Anim. 2019;68:35-47 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig s4
Seipold L, Altmeppen H, Koudelka T, Tholey A, Kaspárek P, Sedlacek R, et al. In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15. Cell Mol Life Sci. 2018;75:3251-3267 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; tbl 1
  • western blot; mouse; 1:1000; loading ...; tbl 1
  • immunocytochemistry; human; 1:100; loading ...; tbl 1
  • western blot; human; 1:1000; loading ...; tbl 1
Lin N, Messing A, Perng M. Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP. PLoS ONE. 2017;12:e0180694 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:50
  • immunohistochemistry; rat; loading ...; fig 107
  • immunohistochemistry - paraffin section; dogs; 1:50
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 1a
Barca Mayo O, Pons Espinal M, Follert P, Armirotti A, Berdondini L, De Pietri Tonelli D. Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling. Nat Commun. 2017;8:14336 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3d
Tirosh I, Venteicher A, Hebert C, Escalante L, Patel A, Yizhak K, et al. Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma. Nature. 2016;539:309-313 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 4f
Menzel L, Kleber L, Friedrich C, Hummel R, Dangel L, Winter J, et al. Progranulin protects against exaggerated axonal injury and astrogliosis following traumatic brain injury. Glia. 2017;65:278-292 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:40,000; fig 2
Wharton K, Quigley C, Themeles M, Dunstan R, Doyle K, Cahir McFarland E, et al. JC Polyomavirus Abundance and Distribution in Progressive Multifocal Leukoencephalopathy (PML) Brain Tissue Implicates Myelin Sheath in Intracerebral Dissemination of Infection. PLoS ONE. 2016;11:e0155897 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 2
Duchnowska R, Pęksa R, Radecka B, Mandat T, Trojanowski T, Jarosz B, et al. Immune response in breast cancer brain metastases and their microenvironment: the role of the PD-1/PD-L axis. Breast Cancer Res. 2016;18:43 pubmed publisher
  • immunohistochemistry; human; 1:200
Okamoto S, Nitta M, Maruyama T, Sawada T, Komori T, Okada Y, et al. Bevacizumab changes vascular structure and modulates the expression of angiogenic factors in recurrent malignant gliomas. Brain Tumor Pathol. 2016;33:129-36 pubmed publisher
  • immunohistochemistry; human; 1:200; fig 2
Pages M, Lacroix L, Tauziède Espariat A, Castel D, Daudigeos Dubus E, Ridola V, et al. Papillary glioneuronal tumors: histological and molecular characteristics and diagnostic value of SLC44A1-PRKCA fusion. Acta Neuropathol Commun. 2015;3:85 pubmed publisher
  • immunohistochemistry; human; 1:50; fig 2
Chen A, Akinyemi R, Hase Y, Firbank M, Ndung u M, Foster V, et al. Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia. Brain. 2016;139:242-58 pubmed publisher
  • immunohistochemistry; human; 1:2000; fig 3
Benítez B, Cairns N, Schmidt R, Morris J, Norton J, Cruchaga C, et al. Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss. Acta Neuropathol Commun. 2015;3:73 pubmed publisher
  • immunohistochemistry; mouse; fig 3c
  • western blot; mouse; fig 3a
Tapia Rojas C, Lindsay C, Montecinos Oliva C, Arrázola M, Retamales R, Bunout D, et al. Is L-methionine a trigger factor for Alzheimer's-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice. Mol Neurodegener. 2015;10:62 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; tbl 2
Li Y, Adomat H, Guns E, Hojabrpour P, Duronio V, Curran T, et al. Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor. J Cell Physiol. 2016;231:1350-63 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:5000
Lechpammer M, Wintermark P, Merry K, Jackson M, Jantzie L, Jensen F. Dysregulation of FMRP/mTOR Signaling Cascade in Hypoxic-Ischemic Injury of Premature Human Brain. J Child Neurol. 2016;31:426-32 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 2
Mellai M, Piazzi A, Casalone C, Grifoni S, Melcarne A, Annovazzi L, et al. Astroblastoma: beside being a tumor entity, an occasional phenotype of astrocytic gliomas?. Onco Targets Ther. 2015;8:451-60 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 8
Altmeppen H, Prox J, Krasemann S, Puig B, Kruszewski K, Dohler F, et al. The sheddase ADAM10 is a potent modulator of prion disease. elife. 2015;4: pubmed publisher
  • immunohistochemistry; human; 1:200
Thompson L, Bauer J, Chiosea S, McHugh J, Seethala R, Miettinen M, et al. Canalicular adenoma: a clinicopathologic and immunohistochemical analysis of 67 cases with a review of the literature. Head Neck Pathol. 2015;9:181-95 pubmed publisher
  • immunohistochemistry; human; 1:200
Hagel C, Krasemann S, Löffler J, Puschel K, Magnus T, Glatzel M. Upregulation of Shiga toxin receptor CD77/Gb3 and interleukin-1? expression in the brain of EHEC patients with hemolytic uremic syndrome and neurologic symptoms. Brain Pathol. 2015;25:146-56 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Schirmer L, Srivastava R, Kalluri S, Böttinger S, Herwerth M, Carassiti D, et al. Differential loss of KIR4.1 immunoreactivity in multiple sclerosis lesions. Ann Neurol. 2014;75:810-28 pubmed publisher
  • immunocytochemistry; human
Nguyen H, Nekanti U, Haus D, Funes G, Moreno D, Kamei N, et al. Induction of early neural precursors and derivation of tripotent neural stem cells from human pluripotent stem cells under xeno-free conditions. J Comp Neurol. 2014;522:2767-83 pubmed publisher
  • immunohistochemistry; human
Toscano M, Butorano M, Cerase A, Miracco C. Correlative study of squash smear cytology with histopathology in a rare case of anaplastic giant cell ependymoma of the pineal. Histol Histopathol. 2014;29:1065-70 pubmed publisher
  • immunohistochemistry - paraffin section; domestic rabbit; 1:200
Liu Z, Yu N, Holz F, Yang F, Stanzel B. Enhancement of retinal pigment epithelial culture characteristics and subretinal space tolerance of scaffolds with 200 nm fiber topography. Biomaterials. 2014;35:2837-50 pubmed publisher
  • immunohistochemistry; domestic rabbit
Kesdangsakonwut S, Sunden Y, Aoshima K, Iwaki Y, Okumura M, Sawa H, et al. Survival of rabid rabbits after intrathecal immunization. Neuropathology. 2014;34:277-83 pubmed publisher
  • immunohistochemistry - paraffin section; human
Ishida M, Iwai M, Yoshida K, Kagotani A, Okabe H. Signet-ring cell melanoma with sentinel lymph node metastasis: A case report with immunohistochemical analysis and review of the clinicopathological features. Oncol Lett. 2014;7:65-68 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:200
Prox J, Bernreuther C, Altmeppen H, Grendel J, Glatzel M, D Hooge R, et al. Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions. J Neurosci. 2013;33:12915-28, 12928a pubmed publisher
  • immunohistochemistry; mouse
Natsume A, Ito M, Katsushima K, Ohka F, Hatanaka A, Shinjo K, et al. Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma. Cancer Res. 2013;73:4559-70 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:5000
Helmy K, Halliday J, Fomchenko E, Setty M, Pitter K, Hafemeister C, et al. Identification of global alteration of translational regulation in glioma in vivo. PLoS ONE. 2012;7:e46965 pubmed publisher
  • immunohistochemistry; mouse; 1:3000
Chen L, Zhang J, Kwok Yan Shum D, Chan Y. Localization of nerve growth factor, neurotrophin-3, and glial cell line-derived neurotrophic factor in nestin-expressing reactive astrocytes in the caudate-putamen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/Bl mice. J Comp Neurol. 2006;497:898-909 pubmed
Kolb J, Tsata V, John N, Kim K, M xf6 ckel C, Rosso G, et al. Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment. Nat Commun. 2023;14:6814 pubmed publisher
Huang Y, Qi L, Kogiso M, Du Y, Braun F, Zhang H, et al. Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion. Adv Sci (Weinh). 2021;8:e2101923 pubmed publisher
Viaene A, Lee E, Rosenbaum J, Nasrallah I, Nasrallah M. Histologic, immunohistochemical, and molecular features of pituicytomas and atypical pituicytomas. Acta Neuropathol Commun. 2019;7:69 pubmed publisher
Jung J, Eggleton P, Robinson A, Wang J, Gutowski N, Holley J, et al. Calnexin is necessary for T cell transmigration into the central nervous system. JCI Insight. 2018;3: pubmed publisher
Rossi M, Saverioni D, Di Bari M, Baiardi S, Lemstra A, Pirisinu L, et al. Atypical Creutzfeldt-Jakob disease with PrP-amyloid plaques in white matter: molecular characterization and transmission to bank voles show the M1 strain signature. Acta Neuropathol Commun. 2017;5:87 pubmed publisher
Welker A, Jaros B, An M, Beattie C. Changes in tumor cell heterogeneity after chemotherapy treatment in a xenograft model of glioblastoma. Neuroscience. 2017;356:35-43 pubmed publisher
Schiffer D, Mellai M, Annovazzi L, Caldera V, Piazzi A, Denysenko T, et al. Stem cell niches in glioblastoma: a neuropathological view. Biomed Res Int. 2014;2014:725921 pubmed publisher
Chan S, Hancox L, Martin Santos A, Loubiere L, Walter M, Gonzalez A, et al. MCT8 expression in human fetal cerebral cortex is reduced in severe intrauterine growth restriction. J Endocrinol. 2014;220:85-95 pubmed publisher
Wen J, Yang H, Zhou B, Lou H, Duan S. ?-Catenin is critical for cerebellar foliation and lamination. PLoS ONE. 2013;8:e64451 pubmed publisher
Vitte J, Traver S, Maués De Paula A, Lesage S, Rovelli G, Corti O, et al. Leucine-rich repeat kinase 2 is associated with the endoplasmic reticulum in dopaminergic neurons and accumulates in the core of Lewy bodies in Parkinson disease. J Neuropathol Exp Neurol. 2010;69:959-72 pubmed publisher
company information
Dako
6392 Via Real
Carpinteria, CA 93013
customer.service.us@dako.com
http://www.dako.com
800-235-5763
headquarters: USA