product summary
company name :
Dako
product type :
antibody
product name :
Desmin
catalog :
M0760
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D33
reactivity :
human, mouse, rat, domestic sheep
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 69
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:20; loading ...; fig 5b
Generali M, Satheesha S, Bode P, Wanner D, Schafer B, Casanova E. High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma. Genes (Basel). 2021;12: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s1b
Maier J, Rogg M, Helmstädter M, Sammarco A, Walz G, Werner M, et al. A Novel Model for Nephrotic Syndrome Reveals Associated Dysbiosis of the Gut Microbiome and Extramedullary Hematopoiesis. Cells. 2021;10: pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 4f
Choi I, Lim H, Cho H, Oh Y, Chou B, Bai H, et al. Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; fig 3c
Dmitrieva R, Lelyavina T, Komarova M, Galenko V, Ivanova O, Tikanova P, et al. Skeletal Muscle Resident Progenitor Cells Coexpress Mesenchymal and Myogenic Markers and Are Not Affected by Chronic Heart Failure-Induced Dysregulations. Stem Cells Int. 2019;2019:5690345 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 3d
Papizan J, Garry G, Brezprozvannaya S, McAnally J, Bassel Duby R, Liu N, et al. Deficiency in Kelch protein Klhl31 causes congenital myopathy in mice. J Clin Invest. 2017;127:3730-3740 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 6i
Jørgensen L, Jepsen P, Boysen A, Dalgaard L, Hvid L, Ørtenblad N, et al. SPARC Interacts with Actin in Skeletal Muscle in Vitro and in Vivo. Am J Pathol. 2017;187:457-474 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6a
  • western blot; mouse; loading ...; fig 6b
Sakata K, Araki K, Nakano H, Nishina T, Komazawa Sakon S, Murai S, et al. Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome. Sci Rep. 2016;6:37200 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1d
Moser G, Weiss G, Sundl M, Gauster M, Siwetz M, Lang Olip I, et al. Extravillous trophoblasts invade more than uterine arteries: evidence for the invasion of uterine veins. Histochem Cell Biol. 2017;147:353-366 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 7a
  • western blot; human; loading ...; fig 8a
Hernandez D, Bennett C, Dunina Barkovskaya L, Wedig T, Capetanaki Y, Herrmann H, et al. Nebulette is a powerful cytolinker organizing desmin and actin in mouse hearts. Mol Biol Cell. 2016;27:3869-3882 pubmed
  • immunohistochemistry - frozen section; mouse; 1:50; fig 1
Su X, Tan Q, Parikh B, Tan A, Mehta M, Sia Wey Y, et al. Characterization of Fatty Acid Binding Protein 7 (FABP7) in the Murine Retina. Invest Ophthalmol Vis Sci. 2016;57:3397-408 pubmed publisher
  • immunohistochemistry - frozen section; human; fig 3
Winter L, Türk M, Harter P, Mittelbronn M, Kornblum C, Norwood F, et al. Downstream effects of plectin mutations in epidermolysis bullosa simplex with muscular dystrophy. Acta Neuropathol Commun. 2016;4:44 pubmed publisher
  • immunocytochemistry; human; tbl 1
Almeida C, Fernandes S, Ribeiro Junior A, Keith Okamoto O, Vainzof M. Muscle Satellite Cells: Exploring the Basic Biology to Rule Them. Stem Cells Int. 2016;2016:1078686 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 4c
Lao X, Liang Y, Su Y, Zhang S, Zhou X, Liao G. Distribution and significance of interstitial fibrosis and stroma-infiltrating B cells in tongue squamous cell carcinoma. Oncol Lett. 2016;11:2027-2034 pubmed
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; tbl 1
Ito M, Nakamura K, Mori F, Miki Y, Tanji K, Wakabayashi K. Novel eosinophilic neuronal cytoplasmic inclusions in the external cuneate nucleus of humans. Neuropathology. 2016;36:441-447 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:200; fig 3
Gurnik S, Devraj K, Macas J, Yamaji M, Starke J, Scholz A, et al. Angiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling. Acta Neuropathol. 2016;131:753-73 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 3
Yamada Y, Yamamoto H, Kohashi K, Ishii T, Iura K, Maekawa A, et al. Histological spectrum of angiofibroma of soft tissue: histological and genetic analysis of 13 cases. Histopathology. 2016;69:459-69 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:80; loading ...; fig 3c
Azoitei N, Becher A, Steinestel K, Rouhi A, Diepold K, Genze F, et al. PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation. Mol Cancer. 2016;15:3 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 2
Scholz A, Harter P, Cremer S, Yalcin B, Gurnik S, Yamaji M, et al. Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma. EMBO Mol Med. 2016;8:39-57 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; tbl 1
Shah F, Berggren D, Holmlund T, Levring Jäghagen E, Stål P. Unique expression of cytoskeletal proteins in human soft palate muscles. J Anat. 2016;228:487-94 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:250; fig 4
Agaimy A, Specht K, Stoehr R, Lorey T, Märkl B, Niedobitek G, et al. Metastatic Malignant Melanoma With Complete Loss of Differentiation Markers (Undifferentiated/Dedifferentiated Melanoma): Analysis of 14 Patients Emphasizing Phenotypic Plasticity and the Value of Molecular Testing as Surrogate Diagnostic Marker. Am J Surg Pathol. 2016;40:181-91 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:800
Morita S, Furube E, Mannari T, Okuda H, Tatsumi K, Wanaka A, et al. Heterogeneous vascular permeability and alternative diffusion barrier in sensory circumventricular organs of adult mouse brain. Cell Tissue Res. 2016;363:497-511 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:250; loading ...; fig 3
Ohlmann C, Brecht I, Junker K, van der Zee J, Nistor A, Bohle R, et al. Sclerosing epithelioid fibrosarcoma of the kidney: clinicopathologic and molecular study of a rare neoplasm at a novel location. Ann Diagn Pathol. 2015;19:221-5 pubmed publisher
  • immunocytochemistry; human; 1:50; fig 2
Chen H, Aksoy I, Gonnot F, Osteil P, Aubry M, Hamela C, et al. Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency. Nat Commun. 2015;6:7095 pubmed publisher
  • immunocytochemistry; human; 1:100
Medel S, Alarab M, Kufaishi H, Drutz H, Shynlova O. Attachment of Primary Vaginal Fibroblasts to Absorbable and Nonabsorbable Implant Materials Coated With Platelet-Rich Plasma: Potential Application in Pelvic Organ Prolapse Surgery. Female Pelvic Med Reconstr Surg. 2015;21:190-7 pubmed publisher
  • immunohistochemistry - paraffin section; rat; fig 7
Lee H, Jeong H, Park S, Yoo W, Choi S, Choi K, et al. Fusion protein of retinol-binding protein and albumin domain III reduces liver fibrosis. EMBO Mol Med. 2015;7:819-30 pubmed publisher
  • immunohistochemistry; human; tbl 1
Xiu Y, Jiang L, Liu W. Classic biphasic pulmonary blastoma with brain and axillary metastases: a case report with molecular analysis and review of literature. Int J Clin Exp Pathol. 2015;8:983-8 pubmed
  • immunohistochemistry - paraffin section; human; 1:100
Alaggio R, Midrio P, Sgrò A, Piovan G, Guzzardo V, Donato R, et al. Congenital diaphragmatic hernia: focus on abnormal muscle formation. J Pediatr Surg. 2015;50:388-93 pubmed publisher
  • western blot; human
Ahmad F, Shen W, Vandeput F, Szabo Fresnais N, Krall J, Degerman E, et al. Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2. J Biol Chem. 2015;290:6763-76 pubmed publisher
  • immunohistochemistry; human; 1:100
  • western blot; human
Fichna J, Karolczak J, Potulska Chromik A, Miszta P, Berdynski M, Sikorska A, et al. Two desmin gene mutations associated with myofibrillar myopathies in Polish families. PLoS ONE. 2014;9:e115470 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Yang Z, Broz D, Noderer W, Ferreira J, Overton K, Spencer S, et al. p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stress. Cell Death Differ. 2015;22:560-73 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:75
Ortega P, Suster D, Falconieri G, Zambrano E, Moran C, Morrison C, et al. Liposarcomas of the posterior mediastinum: clinicopathologic study of 18 cases. Mod Pathol. 2015;28:721-31 pubmed publisher
  • immunohistochemistry; human; 1:400
Chow L. Primary intraosseous hybrid nerve sheath tumor of femur: a hitherto undescribed occurrence in bone with secondary aneurysmal bone cyst formation resulting in pathological fracture. Pathol Res Pract. 2015;211:409-14 pubmed publisher
  • immunohistochemistry; mouse; fig s2
O Hara L, McInnes K, Simitsidellis I, Morgan S, Atanassova N, Slowikowska Hilczer J, et al. Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset Leydig cell apoptosis in both mice and men. FASEB J. 2015;29:894-910 pubmed publisher
  • immunohistochemistry - paraffin section; human
Jeon Y, Moon K, Park S, Chung D. Primary pulmonary myxoid sarcomas with EWSR1-CREB1 translocation might originate from primitive peribronchial mesenchymal cells undergoing (myo)fibroblastic differentiation. Virchows Arch. 2014;465:453-61 pubmed publisher
  • immunocytochemistry; mouse; 1:200
Ma M, Czepiel M, Krause T, Schafer K, Boddeke E, Copray S. Generation of induced pluripotent stem cells from hair follicle bulge neural crest stem cells. Cell Reprogram. 2014;16:307-13 pubmed publisher
  • immunohistochemistry; human
Janbaz A, Lindström M, Liu J, Pedrosa Domellöf F. Intermediate filaments in the human extraocular muscles. Invest Ophthalmol Vis Sci. 2014;55:5151-9 pubmed publisher
  • immunohistochemistry; human; 1:4000
Milione M, Gasparini P, Sozzi G, Mazzaferro V, Ferrari A, Casali P, et al. Ewing sarcoma of the small bowel: a study of seven cases, including one with the uncommonly reported EWSR1-FEV translocation. Histopathology. 2014;64:1014-26 pubmed publisher
  • immunohistochemistry; human; 1:200; loading ...; fig s2b
Gevaert T, Vanstreels E, Daelemans D, Franken J, Van Der Aa F, Roskams T, et al. Identification of different phenotypes of interstitial cells in the upper and deep lamina propria of the human bladder dome. J Urol. 2014;192:1555-63 pubmed publisher
  • immunocytochemistry; human
Srikhajon K, Shynlova O, Preechapornprasert A, Chanrachakul B, Lye S. A new role for monocytes in modulating myometrial inflammation during human labor. Biol Reprod. 2014;91:10 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Mori F, Watanabe Y, Miki Y, Tanji K, Odagiri S, Eto K, et al. Ubiquitin-negative, eosinophilic neuronal cytoplasmic inclusions associated with stress granules and autophagy: an immunohistochemical investigation of two cases. Neuropathology. 2014;34:140-7 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:100
Kabaroff L, Gupta A, Menezes S, Babichev Y, Kandel R, Swallow C, et al. Development of genetically flexible mouse models of sarcoma using RCAS-TVA mediated gene delivery. PLoS ONE. 2014;9:e94817 pubmed publisher
  • western blot; mouse; 1:250; tbl 3
Kammoun M, Picard B, Henry Berger J, Cassar Malek I. A network-based approach for predicting Hsp27 knock-out targets in mouse skeletal muscles. Comput Struct Biotechnol J. 2013;6:e201303008 pubmed publisher
  • immunohistochemistry; human; 1:200
Ciucurel E, Sefton M. Del-1 overexpression in endothelial cells increases vascular density in tissue-engineered implants containing endothelial cells and adipose-derived mesenchymal stromal cells. Tissue Eng Part A. 2014;20:1235-52 pubmed publisher
  • immunohistochemistry; human; 1:50
Yu L, Cheng H, Yang S. Clinicopathological and extensive immunohistochemical study of a type II pleuropulmonary blastoma. Fetal Pediatr Pathol. 2014;33:1-8 pubmed publisher
  • immunocytochemistry; domestic sheep; fig 5
Weber B, Kehl D, Bleul U, Behr L, Sammut S, Frese L, et al. In vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells. J Tissue Eng Regen Med. 2016;10:52-70 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Kubota F, Matsuyama A, Shibuya R, Nakamoto M, Hisaoka M. Desmin-positivity in spindle cells: under-recognized immunophenotype of lipoblastoma. Pathol Int. 2013;63:353-7 pubmed publisher
  • immunohistochemistry; human; 1:400; tbl 1
Lee P, Yau D, Lau P, Chan J. Plexiform fibromyxoma (plexiform angiomyxoid myofibroblastic tumor) of stomach: an unusual presentation as a fistulating abscess. Int J Surg Pathol. 2014;22:286-90 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Schell C, Baumhakl L, Salou S, Conzelmann A, Meyer C, Helmstädter M, et al. N-wasp is required for stabilization of podocyte foot processes. J Am Soc Nephrol. 2013;24:713-21 pubmed publisher
  • immunohistochemistry - paraffin section; human
  • immunocytochemistry; human; 1:50
Kazmi S, Byer S, Eckert J, Turk A, Huijbregts R, Brossier N, et al. Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis. Am J Pathol. 2013;182:646-67 pubmed publisher
  • immunocytochemistry; mouse; 1:100
Valsecchi F, Grefte S, Roestenberg P, Joosten Wagenaars J, Smeitink J, Willems P, et al. Primary fibroblasts of NDUFS4(-/-) mice display increased ROS levels and aberrant mitochondrial morphology. Mitochondrion. 2013;13:436-43 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:75
Criswell T, Corona B, Wang Z, Zhou Y, Niu G, Xu Y, et al. The role of endothelial cells in myofiber differentiation and the vascularization and innervation of bioengineered muscle tissue in vivo. Biomaterials. 2013;34:140-9 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:250
Büttner M, Kufer V, Brunner K, Hartmann A, Amann K, Agaimy A. Benign mesenchymal tumours and tumour-like lesions in end-stage renal disease. Histopathology. 2013;62:229-36 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Kon T, Mori F, Tanji K, Miki Y, Kimura T, Wakabayashi K. Giant cell polymyositis and myocarditis associated with myasthenia gravis and thymoma. Neuropathology. 2013;33:281-7 pubmed publisher
  • immunohistochemistry; human; 1:100
Yamada Y, Yamamoto H, Ohishi Y, Nishiyama K, Fukuhara M, Saitou T, et al. Sclerosing variant of perivascular epithelioid cell tumor in the female genital organs. Pathol Int. 2011;61:768-72 pubmed publisher
Roman W, Martins J, Gomes E. Local Arrangement of Fibronectin by Myofibroblasts Governs Peripheral Nuclear Positioning in Muscle Cells. Dev Cell. 2018;46:102-111.e6 pubmed publisher
Ramirez Martinez A, Cenik B, Bezprozvannaya S, Chen B, Bassel Duby R, Liu N, et al. KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination. elife. 2017;6: pubmed publisher
Jia X, Yang J, Chen L, Yu C. Large cervicothoracic myxoinflammatory fibroblastic sarcoma with brachial plexus invasion: A case report and literature review. Oncol Lett. 2016;12:1717-1720 pubmed
Knudsen K, Nielsen B, Lindebjerg J, Hansen T, Holst R, Sørensen F. microRNA-17 Is the Most Up-Regulated Member of the miR-17-92 Cluster during Early Colon Cancer Evolution. PLoS ONE. 2015;10:e0140503 pubmed publisher
Hettmer S, Bronson R, Wagers A. Distinct malignant behaviors of mouse myogenic tumors induced by different oncogenetic lesions. Front Oncol. 2015;5:50 pubmed publisher
Goodpaster T, Randolph Habecker J. A flexible mouse-on-mouse immunohistochemical staining technique adaptable to biotin-free reagents, immunofluorescence, and multiple antibody staining. J Histochem Cytochem. 2014;62:197-204 pubmed publisher
Rivkin E, Almeida S, Ceccarelli D, Juang Y, MacLean T, Srikumar T, et al. The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature. 2013;498:318-24 pubmed publisher
Majeti B, Lee J, Simmons B, Shojaei F. VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineered mouse model of lung adenocarcinoma. BMC Cancer. 2013;13:213 pubmed publisher
Baker L, Gillis D, Sharma S, Ambrus A, Herrmann H, Conover G. Nebulin binding impedes mutant desmin filament assembly. Mol Biol Cell. 2013;24:1918-32 pubmed publisher
Cui J, Chen S, Zhang C, Meng F, Wu W, Hu R, et al. Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia. Mol Neurodegener. 2012;7:21 pubmed publisher
Luth E, Jun S, Wessen M, Liadaki K, Gussoni E, Kunkel L. Bone marrow side population cells are enriched for progenitors capable of myogenic differentiation. J Cell Sci. 2008;121:1426-34 pubmed publisher
Relaix F, Montarras D, Zaffran S, Gayraud Morel B, Rocancourt D, Tajbakhsh S, et al. Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells. J Cell Biol. 2006;172:91-102 pubmed
Huh M, Parker M, Scime A, Parks R, Rudnicki M. Rb is required for progression through myogenic differentiation but not maintenance of terminal differentiation. J Cell Biol. 2004;166:865-76 pubmed
Kikkawa Y, Virtanen I, Miner J. Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane. J Cell Biol. 2003;161:187-96 pubmed
Asakura A, Seale P, Girgis Gabardo A, Rudnicki M. Myogenic specification of side population cells in skeletal muscle. J Cell Biol. 2002;159:123-34 pubmed
company information
Dako
6392 Via Real
Carpinteria, CA 93013
customer.service.us@dako.com
http://www.dako.com
800-235-5763
headquarters: USA