product summary
company name :
Dako
product type :
antibody
product name :
c-erbB-2 Oncoprotein
catalog :
A0485
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs, cat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 37
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:250; loading ...; fig s2a
Laine A, Nagelli S, Farrington C, Butt U, Cvrljevic A, Vainonen J, et al. CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis. Cancer Res. 2021;81:4319-4331 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1.6 ug/ml; loading ...; fig 3d
Kwon S, Cho C, Kwon Y, Lee E, Park J. A Microfluidic Immunostaining System Enables Quality Assured and Standardized Immunohistochemical Biomarker Analysis. Sci Rep. 2017;7:45968 pubmed publisher
  • western blot; human; loading ...; fig 3a
Andreev J, Thambi N, Perez Bay A, Delfino F, Martin J, Kelly M, et al. Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs. Mol Cancer Ther. 2017;16:681-693 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6c
Lloyd Lewis B, Davis F, Harris O, Hitchcock J, Lourenco F, Pasche M, et al. Imaging the mammary gland and mammary tumours in 3D: optical tissue clearing and immunofluorescence methods. Breast Cancer Res. 2016;18:127 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1a
Day K, Lorenzatti Hiles G, Kozminsky M, Dawsey S, Paul A, Broses L, et al. HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone. Cancer Res. 2017;77:74-85 pubmed publisher
  • immunohistochemistry - paraffin section; rat; loading ...; fig 1
Showler K, Nishimura M, Daino K, Imaoka T, Nishimura Y, Morioka T, et al. Analysis of genes involved in the PI3K/Akt pathway in radiation- and MNU-induced rat mammary carcinomas. J Radiat Res. 2017;58:183-194 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; human; fig s1
Chung I, Reichelt M, Shao L, Akita R, Koeppen H, Rangell L, et al. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016;7:12742 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:250; loading ...; tbl 1
Min L, Zhang C, Ma R, Li X, Yuan H, Li Y, et al. Overexpression of synuclein-? predicts lack of benefit from radiotherapy for breast cancer patients. BMC Cancer. 2016;16:717 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 1b
  • immunocytochemistry; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 1b
Khan S, Sikander M, Ebeling M, Ganju A, Kumari S, Yallapu M, et al. MUC13 interaction with receptor tyrosine kinase HER2 drives pancreatic ductal adenocarcinoma progression. Oncogene. 2017;36:491-500 pubmed publisher
  • western blot; dogs; 1:1000; fig 1a
Gray M, Lee S, McDowell A, Erskine M, Loh Q, Grice O, et al. Dual targeting of EGFR and ERBB2 pathways produces a synergistic effect on cancer cell proliferation and migration in vitro. Vet Comp Oncol. 2017;15:890-909 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 1
de Geus S, Boogerd L, Swijnenburg R, Mieog J, Tummers W, Prevoo H, et al. Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery. Mol Imaging Biol. 2016;18:807-819 pubmed
  • immunohistochemistry - paraffin section; human; 1:400; fig s1
Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed publisher
  • western blot; cat; 1:3500; fig 5b
Soares M, Ribeiro R, Najmudin S, Gameiro A, Rodrigues R, Cardoso F, et al. Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status. Oncotarget. 2016;7:17314-26 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1.28 ug/ml; loading ...; tbl s2
Dupouy D, Ciftlik A, Fiche M, Heintze D, Bisig B, de Leval L, et al. Continuous quantification of HER2 expression by microfluidic precision immunofluorescence estimates HER2 gene amplification in breast cancer. Sci Rep. 2016;6:20277 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500
Nalwoga H, Ahmed L, Arnes J, Wabinga H, Akslen L. Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer. PLoS ONE. 2016;11:e0146823 pubmed publisher
Levi M, Muscatello L, Brunetti B, Benazzi C, Parenti F, Gobbo F, et al. High Intrinsic Expression of P-glycoprotein and Breast Cancer Resistance Protein in Canine Mammary Carcinomas Regardless of Immunophenotype and Outcome. Animals (Basel). 2021;11: pubmed publisher
Roosta Y, Sanaat Z, Nikanfar A, Dolatkhah R, Fakhrjou A. Predictive Value of CD44 for Prognosis in Patients with Breast Cancer. Asian Pac J Cancer Prev. 2020;21:2561-2567 pubmed publisher
Moussa M, Badawy A, Helal N, Hegab F, Youssef M, Aboushousha T, et al. Differential Expression of HER2 and SKP2 in Benign and Malignant Colorectal Lesions. Asian Pac J Cancer Prev. 2020;21:2357-2366 pubmed publisher
Xiao B, Zuo D, Hirukawa A, Cardiff R, Lamb R, Sonenberg N, et al. Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR. Cell Rep. 2020;31:107571 pubmed publisher
Miele E, Abballe L, Spinelli G, Besharat Z, Catanzaro G, Chiacchiarini M, et al. BRAF mutant colorectal cancer: ErbB2 expression levels as predictive factor for the response to combined BRAF/ErbB inhibitors. BMC Cancer. 2020;20:129 pubmed publisher
Vissio E, Metovic J, Osella Abate S, Bertero L, Migliaretti G, Borella F, et al. Integration of Ki-67 index into AJCC 2018 staging provides additional prognostic information in breast tumours candidate for genomic profiling. Br J Cancer. 2020;122:382-387 pubmed publisher
Perkins G, Svrcek M, Bouchet Doumenq C, Voron T, Colussi O, Debove C, et al. Can we classify ampullary tumours better? Clinical, pathological and molecular features. Results of an AGEO study. Br J Cancer. 2019;: pubmed publisher
Iyer P, Shrikhande S, Ranjan M, Joshi A, Gardi N, Prasad R, et al. ERBB2 and KRAS alterations mediate response to EGFR inhibitors in early stage gallbladder cancer. Int J Cancer. 2019;144:2008-2019 pubmed publisher
Yokota T, Serizawa M, Hosokawa A, Kusafuka K, Mori K, Sugiyama T, et al. PIK3CA mutation is a favorable prognostic factor in esophageal cancer: molecular profile by next-generation sequencing using surgically resected formalin-fixed, paraffin-embedded tissue. BMC Cancer. 2018;18:826 pubmed publisher
Hashmi A, Aijaz S, Mahboob R, Khan S, Irfan M, Iftikhar N, et al. Clinicopathologic features of invasive metaplastic and micropapillary breast carcinoma: comparison with invasive ductal carcinoma of breast. BMC Res Notes. 2018;11:531 pubmed publisher
Donzelli S, Milano E, Pruszko M, Sacconi A, Masciarelli S, Iosue I, et al. Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages. Breast Cancer Res. 2018;20:59 pubmed publisher
Mudduwa L, Peiris H, Gunasekara S, Abeysiriwardhana D, Liyanage N, Rayala S, et al. KIBRA; a novel biomarker predicting recurrence free survival of breast cancer patients receiving adjuvant therapy. BMC Cancer. 2018;18:589 pubmed publisher
Mercogliano M, Inurrigarro G, De Martino M, Venturutti L, Rivas M, Cordo Russo R, et al. Invasive micropapillary carcinoma of the breast overexpresses MUC4 and is associated with poor outcome to adjuvant trastuzumab in HER2-positive breast cancer. BMC Cancer. 2017;17:895 pubmed publisher
Halle M, Tangen I, Berg H, Hoivik E, Mauland K, Kusonmano K, et al. HER2 expression patterns in paired primary and metastatic endometrial cancer lesions. Br J Cancer. 2017;: pubmed publisher
Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed publisher
Murawski M, Wozniak M, Duś Szachniewicz K, Kołodziej P, Rzeszutko M, Ziółkowski P. Significance of Matrix Metalloproteinase 9 Expression as Supporting Marker to Cytokeratin 19 mRNA in Sentinel Lymph Nodes in Breast Cancer Patients. Int J Mol Sci. 2016;17: pubmed publisher
Makatsoris T, Tsamandas A, Strimpakos A, Alexopoulou Z, Dionysopoulos D, Pervana S, et al. HER Family Protein Expression in a Greek Population with Gastric Cancer. A Retrospective Hellenic Cooperative Oncology Group Study. Anticancer Res. 2016;36:1581-90 pubmed
Engels C, Kiderlen M, Bastiaannet E, van Eijk R, Mooyaart A, Smit V, et al. The clinical value of HER-2 overexpression and PIK3CA mutations in the older breast cancer population: a FOCUS study analysis. Breast Cancer Res Treat. 2016;156:361-70 pubmed publisher
Zhao L, Liu H, Wei Q, Xu G, Wu J, Xu H, et al. Contrast-Enhanced Ultrasonography Features of Breast Malignancies with Different Sizes: Correlation with Prognostic Factors. Biomed Res Int. 2015;2015:613831 pubmed publisher
Liu W, Wang L, Chen J, Yuan J, Xiang Q, Yang G, et al. Application of multispectral imaging in quantitative immunohistochemistry study of breast cancer: a comparative study. Tumour Biol. 2016;37:5013-24 pubmed publisher
Wege A, Schmidt M, Ueberham E, Ponnath M, Ortmann O, Brockhoff G, et al. Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies. MAbs. 2014;6:968-77 pubmed publisher
company information
Dako
6392 Via Real
Carpinteria, CA 93013
customer.service.us@dako.com
http://www.dako.com
800-235-5763
headquarters: USA