product summary
Loading...
company name :
DIMA Biotechnology
product type :
protein
product name :
Human CSF1R Protein, His Tag
catalog :
PME100067
quantity :
10 μg, 100 μg
price :
60 USD, 298 USD
more info or order :
image
image 1 :
Figure 1. Human CSF1R Protein, His Tag on SDS-PAGE under reducing condition.
product information
Catalog Number :
PME100067
Product Name :
Human CSF1R Protein, His Tag
Product Type :
protein
Size :
10 μg, 100 μg
List Price :
60 USD, 298 USD
Product Description :
Recombinant human CSF1R protein with C-terminal 6×His tag
Background :
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.
Purity :
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 23 % trehalose is added as protectants before lyophilization.
Uses :
Research use only
Application Summary :
Immunogen,WB,Elisa
Storage :
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
more info or order :
company information
DIMA Biotechnology
Wuhan institute of Biotechnology B7
Biolake No.666 Gaoxin Road
Wuhan, Hubei
Biolake No.666 Gaoxin Road
Wuhan, Hubei
info@dimabio.com
https://www.dimabio.com0118615307149771
headquarters: China
DIMA BIOTECH LTD (DIMABIO) focuses exclusively on the pre-clinical research market of Immune Oncology. Currently, we offer functional proteins and recombinant monoclonal antibodies. Our proprietary DimAb™ technology platform can directly clone IgG gene from immunized animal, which is a technology breakthrough in monoclonal antibody development.
All DIMABIOs protein products were manufactured by using mammalian cell expression system. To analyze the function of DIMABIOs proteins, we evaluated them by paired binding test between native ligand-receptor and or the binding capacity to the therapeutic antibodies. For DimAb™ recombinant monoclonal antibodies, we focus mainly on identifying clones with flow and blocking activity.
All DIMABIOs protein products were manufactured by using mammalian cell expression system. To analyze the function of DIMABIOs proteins, we evaluated them by paired binding test between native ligand-receptor and or the binding capacity to the therapeutic antibodies. For DimAb™ recombinant monoclonal antibodies, we focus mainly on identifying clones with flow and blocking activity.