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company name :
DIMA Biotechnology
product type :
protein
product name :
Human TIM3 Protein, mFc-His Tag
catalog :
PME100030
quantity :
10 μg, 100 μg
price :
60 USD, 378 USD
more info or order :
DIMA Biotechnology product webpage
image
image 1 :
DIMA Biotechnology PME100030 image 1
Figure 1. Human TIM3 Protein, mFc-His Tag on SDS-PAGE under reducing condition.
image 2 :
DIMA Biotechnology PME100030 image 2
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human TIM3, mFc-His tagged protein (PME100030) can bind Anti-TIM3 Neutralizing antibody(BME100008) in a linear range of 0.12-6.89 ng/ml.
product information
Catalog Number :
PME100030
Product Name :
Human TIM3 Protein, mFc-His Tag
Product Type :
protein
Size :
10 μg, 100 μg
List Price :
60 USD, 378 USD
Product Description :
Recombinant human TIM3 protein with C-terminal mouse Fc and 6×His tag
Background :
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Purity :
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 23 % trehalose is added as protectants before lyophilization.
Uses :
Research use only
Application Summary :
Immunogen,WB,Elisa
Storage :
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
more info or order :
DIMA Biotechnology product webpage
company information
DIMA Biotechnology
Wuhan institute of Biotechnology B7
Biolake No.666 Gaoxin Road
Wuhan, Hubei
info@dimabio.com
https://www.dimabio.com
0118615307149771
headquarters: China
DIMA BIOTECH LTD (DIMABIO) focuses exclusively on the pre-clinical research market of Immune Oncology. Currently, we offer functional proteins and recombinant monoclonal antibodies. Our proprietary DimAb™ technology platform can directly clone IgG gene from immunized animal, which is a technology breakthrough in monoclonal antibody development.

All DIMABIOs protein products were manufactured by using mammalian cell expression system. To analyze the function of DIMABIOs proteins, we evaluated them by paired binding test between native ligand-receptor and or the binding capacity to the therapeutic antibodies. For DimAb™ recombinant monoclonal antibodies, we focus mainly on identifying clones with flow and blocking activity.