product summary
Loading...
company name :
DIMA Biotechnology
product type :
protein
product name :
Human PD-L1 Protein, mFc-His tag
catalog :
PME100023
quantity :
10 μg, 100 μg
price :
60 USD, 378 USD
more info or order :
DIMA Biotechnology product webpage
image
image 1 :
DIMA Biotechnology PME100023 image 1
Figure 1. Human PD-L1 Protein, mFc-His Tag on SDS-PAGE under reducing condition.
image 2 :
DIMA Biotechnology PME100023 image 2
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD-L1, mFc-His tagged protein (PME100023) can bind Anti-PDL1 Neutralizing antibody (BME100009) in a linear range of 0.24-7.81 ng/ml.
image 3 :
DIMA Biotechnology PME100023 image 3
Figure 3. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, hFc-His tagged protein (PME100462) can bind Human PDL1, mFc-His tagged protein (PME100023) in a linear range of 62.5-251.1 ng/ml.
product information
Catalog Number :
PME100023
Product Name :
Human PD-L1 Protein, mFc-His tag
Product Type :
protein
Size :
10 μg, 100 μg
List Price :
60 USD, 378 USD
Product Description :
Recombinant human PD-L1 protein with C-terminal mouse Fc and 6×His tag
Background :
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
Purity :
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 23 % trehalose is added as protectants before lyophilization.
Uses :
Research use only
Application Summary :
Immunogen,WB,Elisa
Storage :
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
more info or order :
DIMA Biotechnology product webpage
company information
DIMA Biotechnology
Wuhan institute of Biotechnology B7
Biolake No.666 Gaoxin Road
Wuhan, Hubei
info@dimabio.com
https://www.dimabio.com
0118615307149771
headquarters: China
DIMA BIOTECH LTD (DIMABIO) focuses exclusively on the pre-clinical research market of Immune Oncology. Currently, we offer functional proteins and recombinant monoclonal antibodies. Our proprietary DimAb™ technology platform can directly clone IgG gene from immunized animal, which is a technology breakthrough in monoclonal antibody development.

All DIMABIOs protein products were manufactured by using mammalian cell expression system. To analyze the function of DIMABIOs proteins, we evaluated them by paired binding test between native ligand-receptor and or the binding capacity to the therapeutic antibodies. For DimAb™ recombinant monoclonal antibodies, we focus mainly on identifying clones with flow and blocking activity.