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company name :
DIMA Biotechnology
product type :
protein
product name :
Human B7-H3 Protein, mFc-His Tag
catalog :
PME100012
quantity :
10 μg, 100 μg
price :
60 USD, 378 USD
more info or order :
DIMA Biotechnology product webpage
image
image 1 :
DIMA Biotechnology PME100012 image 1
Figure 1. Human B7-H3 Protein, mFc-His Tag on SDS-PAGE under reducing condition.
image 2 :
DIMA Biotechnology PME100012 image 2
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human B7-H3, mFc-His tagged protein (PME100012) can bind Anti-B7-H3 Neutralizing antibody (BME100010) in a linear range of 0.24-31.25 ng/ml.
product information
Catalog Number :
PME100012
Product Name :
Human B7-H3 Protein, mFc-His Tag
Product Type :
protein
Size :
10 μg, 100 μg
List Price :
60 USD, 378 USD
Product Description :
Recombinant human B7-H3 protein with C-terminal mouse Fc and 6×His tag
Background :
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purity :
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer :
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 23 % trehalose is added as protectants before lyophilization.
Uses :
Research use only
Application Summary :
Immunogen,WB,Elisa
Storage :
Store at -80°C for 12 months (Avoid repeated freezing and thawing)
more info or order :
DIMA Biotechnology product webpage
company information
DIMA Biotechnology
Wuhan institute of Biotechnology B7
Biolake No.666 Gaoxin Road
Wuhan, Hubei
info@dimabio.com
https://www.dimabio.com
0118615307149771
headquarters: China
DIMA BIOTECH LTD (DIMABIO) focuses exclusively on the pre-clinical research market of Immune Oncology. Currently, we offer functional proteins and recombinant monoclonal antibodies. Our proprietary DimAb™ technology platform can directly clone IgG gene from immunized animal, which is a technology breakthrough in monoclonal antibody development.

All DIMABIOs protein products were manufactured by using mammalian cell expression system. To analyze the function of DIMABIOs proteins, we evaluated them by paired binding test between native ligand-receptor and or the binding capacity to the therapeutic antibodies. For DimAb™ recombinant monoclonal antibodies, we focus mainly on identifying clones with flow and blocking activity.