Dyberg C, Fransson S, Andonova T, Sveinbjörnsson B, Lännerholm Palm J, Olsen T, et al. Rho-associated kinase is a therapeutic target in neuroblastoma. Proc Natl Acad Sci U S A. 2017;114:E6603-E6612 pubmed publisher

Chen L, DeWispelaere A, Dastvan F, Osborne W, Blechner C, Windhorst S, et al. Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity. PLoS ONE. 2016;11:e0155726 pubmed publisher

Yuan X, Cao J, He X, Serra R, Qu J, Cao X, et al. Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation. Nat Commun. 2016;7:11024 pubmed publisher

Chen W, Delongchamps N, Mao K, Beuvon F, Peyromaure M, Liu Z, et al. High RhoA expression at the tumor front in clinically localized prostate cancer and association with poor tumor differentiation. Oncol Lett. 2016;11:1375-1381 pubmed

Sroka J, Kręcioch I, Zimoląg E, Lasota S, Rak M, Kedracka Krok S, et al. Lamellipodia and Membrane Blebs Drive Efficient Electrotactic Migration of Rat Walker Carcinosarcoma Cells WC 256. PLoS ONE. 2016;11:e0149133 pubmed publisher

Lampi M, Faber C, Huynh J, Bordeleau F, Zanotelli M, Reinhart King C. Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption. PLoS ONE. 2016;11:e0147033 pubmed publisher

Vessieres E, Dib A, Bourreau J, Lelievre E, Custaud M, Lelievre Pegorier M, et al. Long Lasting Microvascular Tone Alteration in Rat Offspring Exposed In Utero to Maternal Hyperglycaemia. PLoS ONE. 2016;11:e0146830 pubmed publisher

He G, Xu W, Li J, Li S, Liu B, Tan X, et al. Huwe1 interacts with Gadd45b under oxygen-glucose deprivation and reperfusion injury in primary Rat cortical neuronal cells. Mol Brain. 2015;8:88 pubmed publisher

Caution K, Gavrilin M, Tazi M, Kanneganti A, Layman D, Hoque S, et al. Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance. Sci Rep. 2015;5:18479 pubmed publisher

Escuin S, Vernay B, Savery D, Gurniak C, Witke W, Greene N, et al. Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure. J Cell Sci. 2015;128:2468-81 pubmed publisher

Breslin J, Zhang X, Worthylake R, Souza Smith F. Involvement of local lamellipodia in endothelial barrier function. PLoS ONE. 2015;10:e0117970 pubmed publisher

Herr M, Mabry S, Jennings L. Tetraspanin CD9 regulates cell contraction and actin arrangement via RhoA in human vascular smooth muscle cells. PLoS ONE. 2014;9:e106999 pubmed publisher

Zhang D, Zhang J, Dai S, Liu S, Liu Y, Tang N, et al. Co-expression of delta-catenin and RhoA is significantly associated with a malignant lung cancer phenotype. Int J Clin Exp Pathol. 2014;7:3724-32 pubmed

Biechler S, Junor L, Evans A, Eberth J, Price R, Potts J, et al. The impact of flow-induced forces on the morphogenesis of the outflow tract. Front Physiol. 2014;5:225 pubmed publisher

Yu Z, Tan J, McMahon A, Iismaa S, Xiao X, Kesteven S, et al. RhoA/ROCK signaling and pleiotropic ?1A-adrenergic receptor regulation of cardiac contractility. PLoS ONE. 2014;9:e99024 pubmed publisher

Filina J, Gabdoulkhakova A, Safronova V. RhoA/ROCK downregulates FPR2-mediated NADPH oxidase activation in mouse bone marrow granulocytes. Cell Signal. 2014;26:2138-46 pubmed publisher

Suen J, Cotterell A, Lohman R, Lim J, Han A, Yau M, et al. Pathway-selective antagonism of proteinase activated receptor 2. Br J Pharmacol. 2014;171:4112-24 pubmed publisher

Gardinier J, Yang W, Madden G, Kronbergs A, Gangadharan V, Adams E, et al. P2Y2 receptors regulate osteoblast mechanosensitivity during fluid flow. Am J Physiol Cell Physiol. 2014;306:C1058-67 pubmed publisher

Marinković G, Kroon J, Hoogenboezem M, Hoeben K, Ruiter M, Kurakula K, et al. Inhibition of GTPase Rac1 in endothelium by 6-mercaptopurine results in immunosuppression in nonimmune cells: new target for an old drug. J Immunol. 2014;192:4370-8 pubmed publisher

de Kreuk B, Schaefer A, Anthony E, Tol S, Fernandez Borja M, Geerts D, et al. The human minor histocompatibility antigen 1 is a RhoGAP. PLoS ONE. 2013;8:e73962 pubmed publisher

Townsend E, Zhang Y, Xu C, Wakita R, Emala C. Active components of ginger potentiate β-agonist-induced relaxation of airway smooth muscle by modulating cytoskeletal regulatory proteins. Am J Respir Cell Mol Biol. 2014;50:115-24 pubmed publisher

Hernandez Hernandez V, Pravincumar P, Diaz Font A, May Simera H, Jenkins D, Knight M, et al. Bardet-Biedl syndrome proteins control the cilia length through regulation of actin polymerization. Hum Mol Genet. 2013;22:3858-68 pubmed publisher

Ramsay A, Evans R, Kiaii S, Svensson L, Hogg N, Gribben J. Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide. Blood. 2013;121:2704-14 pubmed publisher

Yang J, Zhu H, Chen G, Ye Y, Zhao C, Mou Y, et al. Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo. Int J Biochem Cell Biol. 2013;45:657-66 pubmed publisher

Retailleau K, Toutain B, Galmiche G, Fassot C, Sharif Naeini R, Kauffenstein G, et al. Selective involvement of serum response factor in pressure-induced myogenic tone in resistance arteries. Arterioscler Thromb Vasc Biol. 2013;33:339-46 pubmed publisher

Tan H, Biechler S, Junor L, Yost M, Dean D, Li J, et al. Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valves. Dev Biol. 2013;374:345-56 pubmed publisher

Park J, Ryu S, Jung I, Lee Y, Kang K, Lee M, et al. Evaluation of VCAM-1 antibodies as therapeutic agent for atherosclerosis in apolipoprotein E-deficient mice. Atherosclerosis. 2013;226:356-63 pubmed publisher

Yang J, Mou Y, Wu T, Ye Y, Jiang J, Zhao C, et al. Cardiac-specific overexpression of farnesyl pyrophosphate synthase induces cardiac hypertrophy and dysfunction in mice. Cardiovasc Res. 2013;97:490-9 pubmed publisher

Ribeiro A, Sousa B, Carreto L, Mendes N, Nobre A, Ricardo S, et al. P-cadherin functional role is dependent on E-cadherin cellular context: a proof of concept using the breast cancer model. J Pathol. 2013;229:705-18 pubmed publisher

Kalia M, Khasa R, Sharma M, Nain M, Vrati S. Japanese encephalitis virus infects neuronal cells through a clathrin-independent endocytic mechanism. J Virol. 2013;87:148-62 pubmed publisher

Aguilar H, Tracey C, Zielnik B, Mitchell B. Rho-kinase mediates diphosphorylation of myosin regulatory light chain in cultured uterine, but not vascular smooth muscle cells. J Cell Mol Med. 2012;16:2978-89 pubmed publisher

Fang W, Jokar I, Zou A, Lambert D, Dendukuri P, Cheng N. CCL2/CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 protein- and p42/44 mitogen-activated protein kinase (MAPK)-dependent mechanisms. J Biol Chem. 2012;287:36593-608 pubmed publisher

Ramsay A, Clear A, Fatah R, Gribben J. Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer. Blood. 2012;120:1412-21 pubmed publisher

Ridgway L, Wetzel M, Ngo J, Erdreich Epstein A, Marchetti D. Heparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells. Mol Cancer Res. 2012;10:689-702 pubmed publisher

Chen G, Chen S, Wang X, Ding X, Ding J, Meng L. Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells. J Biol Chem. 2012;287:12132-41 pubmed publisher

Chen S, Liu J, Wang X, Liang C, Ding J, Meng L. Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR. Biochem Pharmacol. 2012;83:1183-94 pubmed publisher

DiPaolo B, Margulies S. Rho kinase signaling pathways during stretch in primary alveolar epithelia. Am J Physiol Lung Cell Mol Physiol. 2012;302:L992-1002 pubmed publisher

McAuley E, Bradke T, Plopper G. Phenylboronic acid is a more potent inhibitor than boric acid of key signaling networks involved in cancer cell migration. Cell Adh Migr. 2011;5:382-6 pubmed publisher

ElAli A, Hermann D. Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cells. Brain Pathol. 2012;22:175-87 pubmed publisher

Aguilar H, Tracey C, Tsang S, McGinnis J, Mitchell B. Phos-tag-based analysis of myosin regulatory light chain phosphorylation in human uterine myocytes. PLoS ONE. 2011;6:e20903 pubmed publisher

Winzeler A, Mandemakers W, Sun M, Stafford M, Phillips C, Barres B. The lipid sulfatide is a novel myelin-associated inhibitor of CNS axon outgrowth. J Neurosci. 2011;31:6481-92 pubmed publisher

Ridgway L, Wetzel M, Marchetti D. Heparanase Modulates Shh and Wnt3a Signaling in Human Medulloblastoma Cells. Exp Ther Med. 2011;2:229-238 pubmed

Lima V, Giachini F, Carneiro F, Carvalho M, Fortes Z, Webb R, et al. O-GlcNAcylation contributes to the vascular effects of ET-1 via activation of the RhoA/Rho-kinase pathway. Cardiovasc Res. 2011;89:614-22 pubmed publisher

Céspedes Rubio A, Jurado F, Cardona Gómez G. p120 catenin/?N-catenin are molecular targets in the neuroprotection and neuronal plasticity mediated by atorvastatin after focal cerebral ischemia. J Neurosci Res. 2010;88:3621-34 pubmed publisher

Romero A, Esteban Pretel G, Marin M, Ponsoda X, Ballestín R, Canales J, et al. Chronic ethanol exposure alters the levels, assembly, and cellular organization of the actin cytoskeleton and microtubules in hippocampal neurons in primary culture. Toxicol Sci. 2010;118:602-12 pubmed publisher

Ridgway L, Wetzel M, Marchetti D. Modulation of GEF-H1 induced signaling by heparanase in brain metastatic melanoma cells. J Cell Biochem. 2010;111:1299-309 pubmed publisher

Fang X, Neyrinck A, Matthay M, Lee J. Allogeneic human mesenchymal stem cells restore epithelial protein permeability in cultured human alveolar type II cells by secretion of angiopoietin-1. J Biol Chem. 2010;285:26211-22 pubmed publisher

Rajasekharan S, Bin J, Antel J, Kennedy T. A central role for RhoA during oligodendroglial maturation in the switch from netrin-1-mediated chemorepulsion to process elaboration. J Neurochem. 2010;113:1589-97 pubmed publisher

Franco D, Rezaval C, Caceres A, Schinder A, Ceriani M. ENA/VASP downregulation triggers cell death by impairing axonal maintenance in hippocampal neurons. Mol Cell Neurosci. 2010;44:154-64 pubmed publisher

Rebillard A, Jouan Lanhouet S, Jouan E, Legembre P, Pizon M, Sergent O, et al. Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells. Eur J Cancer. 2010;46:1445-55 pubmed publisher

Liu Y, Li Q, Miao Y, Xu H, Dai S, Wei Q, et al. Ablation of p120-catenin enhances invasion and metastasis of human lung cancer cells. Cancer Sci. 2009;100:441-8 pubmed publisher

Von Zee C, Richards M, Bu P, Perlman J, Stubbs E. Increased RhoA and RhoB protein accumulation in cultured human trabecular meshwork cells by lovastatin. Invest Ophthalmol Vis Sci. 2009;50:2816-23 pubmed publisher

Liu Y, Dong Q, Zhao Y, Dong X, Miao Y, Dai S, et al. P120-catenin isoforms 1A and 3A differently affect invasion and proliferation of lung cancer cells. Exp Cell Res. 2009;315:890-8 pubmed publisher

Moore S, Correia J, Lai Wing Sun K, Pool M, Fournier A, Kennedy T. Rho inhibition recruits DCC to the neuronal plasma membrane and enhances axon chemoattraction to netrin 1. Development. 2008;135:2855-64 pubmed publisher

Gien J, Seedorf G, Balasubramaniam V, Tseng N, Markham N, Abman S. Chronic intrauterine pulmonary hypertension increases endothelial cell Rho kinase activity and impairs angiogenesis in vitro. Am J Physiol Lung Cell Mol Physiol. 2008;295:L680-7 pubmed publisher

Montezano A, Callera G, Yogi A, He Y, Tostes R, He G, et al. Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways. Arterioscler Thromb Vasc Biol. 2008;28:1511-8 pubmed publisher

Petroll W, Ma L, Ly L, Vishwanath M. Analysis of the pattern of subcellular force generation by corneal fibroblasts after Rho activation. Eye Contact Lens. 2008;34:65-70 pubmed publisher

Kim A, Matthew Petroll W. Microtubule regulation of corneal fibroblast morphology and mechanical activity in 3-D culture. Exp Eye Res. 2007;85:546-56 pubmed

Lakshman N, Kim A, Bayless K, Davis G, Petroll W. Rho plays a central role in regulating local cell-matrix mechanical interactions in 3D culture. Cell Motil Cytoskeleton. 2007;64:434-45 pubmed