product summary
Loading...
company name :
Creative Diagnostics
product type :
protein
product name :
S. aureus Enterotoxin Type B Toxoid
catalog :
DAGB111
quantity :
1 mg
more info or order :
Creative Diagnostics product webpage
product information
Catalog :
DAGB111
proudctName :
S. aureus Enterotoxin Type B Toxoid
common :
SEB
Short Name :
S. aureus Enterotoxin Type B Toxoid
Source/Host :
S. aureus
Common name :
SEB
Conjugate :
Unconjugated
Application :
ELISA
Size :
1 mg
Storage :
Store at 2-8°C prior to reconstitution. Following reconstitution, aliquot and freeze.
Antigen Description :
Staphylococcal enterotoxins B (SEB) is described as a superantigen for its ability to bind to Major Histocompatibility Complex molecules on antigen presenting cells and stimulate a large population of T cells, producing an inappropriate flood of cytokines. Although they are important participants in an immune response, cytokines, when overproduced, lead to toxic shock. Recently SEB has been found to bind to another regulator of the T cell immune response, CD 28. When added to human peripheral blood cells, SEB produces large quantities of IL-2, TNF-A and INF-c. Native SEB toxin has been treated with formaldehyde to produce a toxoid which has reduced cytokine stimulating activity and immunogenicity when compared with the native toxin. Care must be taken in the design of experiments with the toxoid because although toxicity has been reduced, sufficient toxicity may remain to cause death under certain conditions. Both the toxin and toxoid are handled as Select Agents and Toxins.
Reconstitution :
Reconstituted with sterile deionized or distilled water
Format :
Lyophilized power
Alternative Names :
EntB;Enterotoxin type B;SEB;Staph. aureus Enterotoxin B ;entB;entC1;entC2;entD;Enterotoxin type B;Enterotoxin type C-1;Staphylococcus Enterotoxin B
Type :
Native
Endotoxin :
The endotoxin content, determined using a kinetic chromogenic LAL assay, is approximately 2 EU/mg.
applicatons :
ELISA
Species :
S. aureus
Molecular Weight :
28 kDa
more info or order :
Creative Diagnostics product webpage
company information
Creative Diagnostics
NY, USA
contact@creative-diagnostics.com
http://www.creative-diagnostics.com
1-631-624-4882
headquarters: USA
Creative Diagnostics is a leading manufacturer and supplier of antibodies, viral antigens, innovative diagnostic components, and critical assay reagents. We provide contract biologic R&D and manufacturing services to the diagnostic manufacturers along with GMP biologics manufacturing for the biopharmaceutical market. Our goal is to be a trusted source for all your assay development and manufacturing needs.
We also assist clients with rapidly developing, manufacturing, and commercializing point of care lateral flow, flow through, and ELISA assays. Our specialties are producing fluorescent, visual colloidal gold, and paramagnetic labels, and highly sensitive, quantitative, and reader-based tests.
With decades of experiences and our unique technologies, Creative Diagnostics is committed to providing its customers the highest quality products and services.