product summary
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company name :
Creative Diagnostics
product type :
protein
product name :
Native Human Uromodulin
catalog :
DAG-IV08
quantity :
10 μg, 1 mg
more info or order :
Creative Diagnostics product webpage
product information
Catalog :
DAG-IV08
proudctName :
Native Human Uromodulin
common :
UMOD
Short Name :
Human Uromodulin
Source/Host :
Human urine
Common name :
UMOD
Conjugate :
unconjugated
Application :
WB, ELISA
Size :
10 μg, 1 mg
Storage :
Store the lyophilized protein at –80 °C. Lyophilized protein remains stable until the expiry date when stored at –80 °C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at –80 °C for long term storage. Reconstituted protein can be stored at 4 °C for a week.
Reconstitution :
Add water for injection to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Format :
Lyophilized
Alternative Names :
UMOD; uromodulin; THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2; uromucoid; Tamm-Horsfall urinary glycoprotein
Buffer :
Filtered (0.4 μm) and lyophilized from 0.5 mg/mL in water for injection.
Purity :
> 95% as determined by SDS-PAGE
Type :
Native
Endotoxin :
0.1 EU/μg
Introduction :
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.
Keywords :
UMOD; uromodulin; THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADMCKD2; uromucoid; Tamm-Horsfall urinary glycoprotein
Product Overview :
Native protein isolated from human urine, 590 AA, 64.265 kDa (calculated without glycosylation). Protein identity confirmed by LC-MS/MS.
applicatons :
WB, ELISA
Species :
Human
Molecular Weight :
64.265 kDa
more info or order :
Creative Diagnostics product webpage
company information
Creative Diagnostics
NY, USA
contact@creative-diagnostics.com
http://www.creative-diagnostics.com
1-631-624-4882
headquarters: USA
Creative Diagnostics is a leading manufacturer and supplier of antibodies, viral antigens, innovative diagnostic components, and critical assay reagents. We provide contract biologic R&D and manufacturing services to the diagnostic manufacturers along with GMP biologics manufacturing for the biopharmaceutical market. Our goal is to be a trusted source for all your assay development and manufacturing needs.
We also assist clients with rapidly developing, manufacturing, and commercializing point of care lateral flow, flow through, and ELISA assays. Our specialties are producing fluorescent, visual colloidal gold, and paramagnetic labels, and highly sensitive, quantitative, and reader-based tests.
With decades of experiences and our unique technologies, Creative Diagnostics is committed to providing its customers the highest quality products and services.