product summary
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company name :
Creative Diagnostics
product type :
antibody
product name :
Chimeric Human Anti-PEG monoclonal antibody, clone Dbhq5
catalog :
CABT-L3141
quantity :
50 μg
clonality :
monoclonal
host :
human
conjugate :
nonconjugated
clone name :
dBHQ5
application :
ELISA
more info or order :
Creative Diagnostics product webpage
product information
Catalog :
CABT-L3141
proudctName :
Chimeric Human Anti-PEG monoclonal antibody, clone Dbhq5
common :
PEG
Short Name :
PEG antibody
Source/Host :
Human
Html Name :
Anti-PEG monoclonal antibody
Html subtitle :
Chimeric Human Anti-PEG monoclonal antibody for ELISA
Common name :
PEG
Conjugate :
Unconjugated
Application :
ELISA
Application Notes :
This item can be used as a IgM reference standard for anti-PEG antibodies. This product contains sufficient material to produce about 300 standard curves at the recommended dilutions.
Antibody Isotype :
IgM
Size :
50 μg
Storage :
Long time storage is recommended at -20°C.
Specificity :
This is a chimeric antibody composed of the BHQ5 anti-PEG variable region genes fused to human IgM constant domains. It is expressed with the human J-chain to form pentamers.
Target :
This antibody binds to the backbone of PEG and can be detected with anti-human secondary antibodies.
Clone :
dBHQ5
Purification :
Affinity Purified
Alternative Names :
Polyetheylene Glycol; PEG
Format :
Liquid
Concentration :
Lot specific
Buffer :
Purified antibdoy supplied in 50% glycerol and phosphate buffered saline (0.14 M NaCl, 2.7 mM KCl, 1.5 mM KH2PO4, 8.1 mM Na2HPO4)
Preservative :
0.04% Sodium Azide
Ship :
Dry ice
Warning :
For research use only.
Introduction :
PEG (polyethylene glycol) is a water-soluble, nontoxic, biocompatible polymer that has been approved by the Food and Drug Administration (FDA) for human intravenous, oral and dermal applications. Attachment of PEG chains to proteins can reduce their immunogenicity, minimize proteolytic cleavage and increase their serum half-life. PEG has also been attached to small molecules and liposomes for more selective delivery. PEG-modification of superparamagnetic iron oxide and quantum dots can improve their biocompatibility and reduce non-specific uptake. PEG antibodies can be a vital tool for propelling therapeutics to market by serving as a positive control anti-drug antibody, measuring clearance of a drug, or simply as a QA release confirming PEGylation.
Keywords :
Polyetheylene Glycol; PEG
Product Overview :
Fusion protein of mouse BHQ5 VH and VL with human IgM
applicatons :
ELISA
Clonality :
Monoclonal
General Notes :
This antibody binds to the repeating subunits of the polyethylene glycol (PEG) backbone and the minimum PEG size that can be bound is ~750 Da. Effective binding is greatly enhanced in PEG conjugates such as PEG-proteins, PEG-liposomes, PEG-cells and PEG-nanoparticles.
Key Features and Details :
Suitable for ELISA Specificity: Polyethylene glycol (PEG) Isotype: IgM Clonality: Monoclonal
more info or order :
Creative Diagnostics product webpage
company information
Creative Diagnostics
NY, USA
contact@creative-diagnostics.com
http://www.creative-diagnostics.com
1-631-624-4882
headquarters: USA
Creative Diagnostics is a leading manufacturer and supplier of antibodies, viral antigens, innovative diagnostic components, and critical assay reagents. We provide contract biologic R&D and manufacturing services to the diagnostic manufacturers along with GMP biologics manufacturing for the biopharmaceutical market. Our goal is to be a trusted source for all your assay development and manufacturing needs.
We also assist clients with rapidly developing, manufacturing, and commercializing point of care lateral flow, flow through, and ELISA assays. Our specialties are producing fluorescent, visual colloidal gold, and paramagnetic labels, and highly sensitive, quantitative, and reader-based tests.
With decades of experiences and our unique technologies, Creative Diagnostics is committed to providing its customers the highest quality products and services.