product summary
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company name :
Creative Diagnostics
product type :
antibody
product name :
Mouse Anti-PNU-159682 monoclonal antibody, clone G8G3
catalog :
CABT-L3111
quantity :
100 μl, 500 μl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G8G3
application :
ELISA
more info or order :
Creative Diagnostics product webpage
product information
Catalog :
CABT-L3111
proudctName :
Mouse Anti-PNU-159682 monoclonal antibody, clone G8G3
common :
PNU-159682
Short Name :
PNU-159682 antibody
Source/Host :
Mouse
Html Name :
Anti-PNU-159682 monoclonal antibody
Html subtitle :
Mouse Anti-PNU-159682 monoclonal antibody for ELISA
Common name :
PNU-159682
Conjugate :
Unconjugated
Application :
ELISA
Application Notes :
Optimal dilutions for each application to be determined by the researcher. Prepare working dilution immediately before use.
Antibody Isotype :
IgG
Size :
100 μl, 500 μl
Storage :
For short term storage, store at 4°C up to 6 months from date of opening or thawing. Long time storage is recommended at -20°C. Avoid repeated freeze-thaw cycles.
Target :
PNU-159682
Clone :
G8G3
Purification :
Antibody was produced by ascites and then isolated via Protein A/G chromatography
BSA :
1% BSA
Alternative Names :
PNU159682; PNU 159682
Format :
Liquid
Concentration :
0.5 mg/ml
Buffer :
PBS
Preservative :
0.02% Sodium Azide
Ship :
Dry ice
Warning :
For research use only.
Introduction :
PNU-159682 is a major bioactive metabolite of Nemorubicin in human liver microsomes;> 3,000-fold cytotoxic than its parent compound(MMDX and doxorubicin). PNU-159682 inhibits a panel of human tumor cell lines with IC70 values in the range of 0.07-0.58 nM, and is 2,360- to 790-fold and 6,420- to 2,100-fold more potent than MMDX and doxorubicin, respectively. PNU-159682 (100 μM) weakly inhibits topoisomerase II unknotting activity. PNU-159682 (10 μM)-DNA adducts contain one or two drug molecules bound to double-stranded DNA. PNU-159682 shows cytotoxic effect on CAIX-expressing SKRC-52 cells with IC50 of 25 nM.
Keywords :
PNU159682;PNU 159682
Official Symbol :
PNU-159682
Product Overview :
Mouse Anti-PNU-159682 mAb
applicatons :
ELISA
Clonality :
Monoclonal
more info or order :
Creative Diagnostics product webpage
company information
Creative Diagnostics
NY, USA
contact@creative-diagnostics.com
http://www.creative-diagnostics.com
1-631-624-4882
headquarters: USA
Creative Diagnostics is a leading manufacturer and supplier of antibodies, viral antigens, innovative diagnostic components, and critical assay reagents. We provide contract biologic R&D and manufacturing services to the diagnostic manufacturers along with GMP biologics manufacturing for the biopharmaceutical market. Our goal is to be a trusted source for all your assay development and manufacturing needs.
We also assist clients with rapidly developing, manufacturing, and commercializing point of care lateral flow, flow through, and ELISA assays. Our specialties are producing fluorescent, visual colloidal gold, and paramagnetic labels, and highly sensitive, quantitative, and reader-based tests.
With decades of experiences and our unique technologies, Creative Diagnostics is committed to providing its customers the highest quality products and services.