product summary
Loading...
company name :
Creative Diagnostics
product type :
antibody
product name :
Mouse anti-Human PI4-Kinase β monoclonal antibody, clone 8/QJ5
catalog :
CABT-B9291
quantity :
50 μg, 150 μg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8/QJ5
application :
western blot
more info or order :
Creative Diagnostics product webpage
product information
Catalog :
CABT-B9291
proudctName :
Mouse anti-Human PI4-Kinase β monoclonal antibody, clone 8/QJ5
common :
PI4KB
Short Name :
PI4-Kinase β antibody
Source/Host :
Mouse
Html Name :
Mouse anti-PI4-Kinase β monoclonal antibody
Html subtitle :
Mouse anti-Human PI4-Kinase β monoclonal antibody for WB, Bioimaging
Common name :
PI4KB
Species :
Human
Conjugate :
Unconjugated
Application :
WB, Bioimaging
Immunogen :
Human PI4Kβ aa. 411-626
Antibody Isotype :
IgG2a
Size :
50 μg, 150 μg
Storage :
Store undiluted at -20°C.
Species Reactivity :
Human, Mouse, Rat, Dog
Clone :
8/QJ5
Purification :
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Alternative Names :
PI4KB; phosphatidylinositol 4-kinase, catalytic, beta; NPIK; PI4K92; PIK4CB; PI4KBETA; PI4K-BETA; PI4KIIIBETA; phosphatidylinositol 4-kinase beta; PtdIns 4-kinase beta; type III phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase, wortmannin-sensitive;
Format :
Liquid
Concentration :
250 μg/ml
Buffer :
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Introduction :
Phosphoinositide turnover is a well established mechanism of intracellular signal transduction. Sequential phosphorylation of phosphatidylinositol (PtdIns) results inPtdIns-4-phosphate (PIP) and PtdIns-4, 5-bisphosphate (PIP2). Phospholipase C (PLC)hydrolyzes PIP2 to inositol-1, 4, 5-trisphosphate (IP3) which stimulates release of intracellular Ca2+. PIP is generated by phosphorylation of PtdIns at the D4 position of the inositol ring. This event is mediated by the PtdIns 4-kinases (PI4-K). These enzymes are divided into two types (II and III) based on their size and sensitivity to certain compounds. Although the PI4-Ks are abundantly distributed throughout the cell, activity is found primarily in association with membranous structures. Members of this family contain a lipid kinase unique domain and a C-terminal catalytic domain. Two mammalian PI4-Ks, PI4-Kα and PI4-Kβ, have been identified. PI4-Kβ is homologous to the yeast PI4-K, PIK1. Based on its size and sensitivity to wortmanin (a PI3-K inhibitor), PI4-Kβ is classified as a type III enzyme. Although it is found in the cytosol and in association with the Golgi, the specific function of PI4-Kβ is yet to be determined.
Keywords :
PI4KB; phosphatidylinositol 4-kinase, catalytic, beta; NPIK; PI4K92; PIK4CB; PI4KBETA; PI4K-BETA; PI4KIIIBETA; phosphatidylinositol 4-kinase beta; PtdIns 4-kinase beta; type III phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase, wortmannin-sensitive;
applicatons :
WB; Bioimaging
Clonality :
Monoclonal
more info or order :
Creative Diagnostics product webpage
company information
Creative Diagnostics
NY, USA
contact@creative-diagnostics.com
http://www.creative-diagnostics.com
1-631-624-4882
headquarters: USA
Creative Diagnostics is a leading manufacturer and supplier of antibodies, viral antigens, innovative diagnostic components, and critical assay reagents. We provide contract biologic R&D and manufacturing services to the diagnostic manufacturers along with GMP biologics manufacturing for the biopharmaceutical market. Our goal is to be a trusted source for all your assay development and manufacturing needs.
We also assist clients with rapidly developing, manufacturing, and commercializing point of care lateral flow, flow through, and ELISA assays. Our specialties are producing fluorescent, visual colloidal gold, and paramagnetic labels, and highly sensitive, quantitative, and reader-based tests.
With decades of experiences and our unique technologies, Creative Diagnostics is committed to providing its customers the highest quality products and services.