This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human TNFRSF4
catalog :
TNFRSF4-967H
product information
Cat :
TNFRSF4-967H
Product Name :
Recombinant Human TNFRSF4
Brand :
Creative Biomart
gene symbal :
TNFRSF4
gene name :
tumor necrosis factor receptor superfamily, member 4
Synonyms :
TNFRSF4; tumor necrosis factor receptor superfamily, member 4; tumor necrosis factor receptor superfamily member 4; OX40 antigen; OX40L receptor; tax-transcriptionally activated glycoprotein 1; Ox40; ACT35; CD134; Ly-70; Txgp1; TXGP1L
Product Overview :
Recombinant human OX40L produced inInsect cellsis a glycosylated 133 amino acid protein corresponding to the extracellular TNF homologous domain of the full length transmembrane protein. It migrates with an apparent molecular mass of 15.5 25.0 kDa on SDS-PAGE.
Description :
Recombinant human OX40L produced inInsect cellsis a glycosylated 133 amino acid protein corresponding to the extracellular TNF homologous domain of the full length transmembrane protein. It migrates with an apparent molecular mass of 15.5 25.0 kDa on SDS-PAGE.OX40L, a member of the TNF superfamily of structurally related proteins, exists primarily as a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells (APCs), such as dendritic cells and activated B-cells, and also on various other cells such as vascular endothelial cells, mast cells, and natural killer cells. OX40L signals specifically through the OX40 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX40/OX40L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFN . OX40/OX40L signaling plays an important role in immuno-regulatory communication, enabling the immune system to distinguish between friend vs. foe during activation; a mechanism typically termed immuno-tolerance.
Source :
Insect cells
Purity :
97%, by SDS-PAGE and HPLC analysis.
UniProt ID :
P43489
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
questions and comments