This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human SMAD Family Member 3, GST-tagged
catalog :
SMAD3-1491H
product information
Cat :
SMAD3-1491H
Product Name :
Recombinant Human SMAD Family Member 3, GST-tagged
Brand :
Creative Biomart
gene symbal :
SMAD3
gene name :
SMAD3 SMAD family member 3 [ Homo sapiens ]
Synonyms :
SMAD3; SMAD family member 3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436; MGC60396; DKFZp586N0721; DKFZp686J10186; mothers against decapentaplegic homolog 3; mad3; hMAD-3; hSMAD3; MAD homolog 3; OTTHUMP00000164305; mad homolog JV15-2; mad protein homolog; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD, mothers against DPP homolog 3; MAD, mothers against decapentaplegic homolog 3; MAD, mothers against decapentaplegic homolog 3 (Drosophila); SMAD, mothers against DPP homolog 3 (Drosophila); Mothers against decapentaplegic homolog 3; Mothers against DPP homolog 3; Smad3
Product Overview :
Recombinant full-length human SMAD3 was expressed in E. coli cells using an N-terminal GST tag.
Description :
SMAD3 is a direct mediator of transcriptional activation by the TGFβ receptor. The activity of SMAD3 is regulated by the TGFβ receptors, and SMAD3 is phosphorylated and associated with the ligand-bound receptor complex. TGFβ stimulation leads to phosphorylation and activation of SMAD3, which form a complex with SMAD4 that accumulate in the nucleus and regulate transcription of target genes such as CDK inhibitor.
Form :
Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1mM PMSF, 25 % glycerol.
Purity :
90 %
Concentration :
0.2 ug/ul
Storage :
Store product at -70 C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
UniProt ID :
P84022
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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