This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human SIGIRR, Fc Chimera
catalog :
SIGIRR-2422H
product information
Cat :
SIGIRR-2422H
Product Name :
Recombinant Human SIGIRR, Fc Chimera
Brand :
Creative Biomart
gene symbal :
SIGIRR
gene name :
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
Synonyms :
SIGIRR; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single Ig IL-1-related receptor; single immunoglobulin domain IL1R1 related; TIR8; Single immunoglobulin domain containing IL1R related protein; Toll/interleukin 1 receptor 8; Ig IL1 related receptor; MGC110992; SIGIR_HUMAN; Single Ig IL 1 related receptor; Single Ig IL-1R-related molecule; Single Ig IL1R Related Molecule; Single immunoglobulin and toll interleukin 1 receptor (TIR) domain; Single immunoglobulin and toll interleukin 1 receptor domain; Single immunoglobulin domain-containing IL1R-related protein; TIR 8; Toll/interleukin-1 receptor 8; OTTHUMP00000229641; OTTHUMP00000229642; OTTHUMP00000229643; OTTHUMP00000229644; OTTHUMP00000229645; single immunoglobulin
Product Overview :
Recombinant signal peptide and extracellular domain of human SIGIRR (aa 1-118) produced inHEK 293 cellsare fused at the C-terminus to the Fc portion of human IgG.
Description :
Recombinant signal peptide and extracellular domain of human SIGIRR (aa 1-118) produced inHEK 293 cellsare fused at the C-terminus to the Fc portion of human IgG.Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, also known as SIGIRR is a member of the IL-1 receptor family. It acts as a negative regulator of interleukin (IL)-1 and lipopolysaccharide (LPS) signaling. It also plays a critical role in gut homeostasis, intestinal inflammation, and colitis-associated tumorigenesis by maintaining the microbial tolerance of the colonic epithelium.
Purity :
≥90% (SDS-PAGE).
UniProt ID :
Q6IA17
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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