This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human SERPINF1, FLAG-tagged
catalog :
SERPINF1-25H
product information
Cat :
SERPINF1-25H
Product Name :
Recombinant Human SERPINF1, FLAG-tagged
Brand :
Creative Biomart
gene symbal :
SERPINF1
gene name :
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Synonyms :
SERPINF1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; OI6; OI12; PEDF; EPC-1; PIG35; pigment epithelium-derived factor; serpin F1; cell proliferation-inducing gene 35 protein; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1;
Product Overview :
Recombinant Human SERPINF1produced inHEK293 cellsis a single, glycosylated, polypeptide chain containing 410 amino acids and having a molecular mass of 45.6 kDa. The Human Sentrin-F1 is fused to FLAG tag at N-Terminus. The Human PEDF is purified by proprietary chromatographic techniques.
Description :
Recombinant Human SERPINF1produced inHEK293 cellsis a single, glycosylated, polypeptide chain containing 410 amino acids and having a molecular mass of 45.6 kDa. The Human Sentrin-F1 is fused to FLAG tag at N-Terminus. The Human PEDF is purified by proprietary chromatographic techniques.PEDF is a neurotrophic protein that induces extensive neuronal differentiation in retinoblastoma cells. SerpinF1 is a potent inhibitor of angiogenesis. EPC1 doesn"t undergo the stressed to relaxed conformation transition characteristic as of the active serpins since it exhibits no serine protease inhibitory activity. Aqueous humour level of asymmetric dimethylarginine is correlated with PEDF in humans. PEDF and VEGF structural changes in blood vessel wall play an important role in the pathophysiology of PD patients. PEDF-overexpressing tumors exhibited reduced intratumoral angiogenesis. SerpinF1 is a new promising approach for the treatment of osteosarcoma. Levels of the natural ocular anti-angiogenic factor SentrinF1 (PEDF) is associated with proliferative retinopathy. PEDF blocks angiogenic effects of leptin through its anti-oxidative properties.
Source :
HEK 293
Purity :
Greater than 95% as determined by SDS-PAGE.
Storage :
Store lyophilized protein at -20 C . Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 C for a limited period of time.
UniProt ID :
P36955
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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