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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Prolactin Receptor, Fc-tagged
catalog :
PRLR-1677H
product information
Cat :
PRLR-1677H
Product Name :
Recombinant Human Prolactin Receptor, Fc-tagged
Brand :
Creative Biomart
gene symbal :
PRLR
gene name :
prolactin receptor
Synonyms :
PRLR; prolactin receptor; HPRL; MFAB; hPRLrI; PRL-R; hPRL receptor; secreted prolactin binding protein;
Product Overview :
Recombinant Human PRLR was expressed inNSOcells. The DNA sequence encoding the signal peptide from human CD33 joined with the extracellular domain of human Prolactin R was fused to the Fc region of human IgG1 via a linker peptide.
Description :
Recombinant Human PRLR was expressed inNSOcells. The DNA sequence encoding the signal peptide from human CD33 joined with the extracellular domain of human Prolactin R was fused to the Fc region of human IgG1 via a linker peptide.Prolactin Receptor (PRLR) is a cytokine receptor superfamily that lacks an intrinsic kinase domain and relies on the cytoplasmic Jak tyrosine kinases to transduce signals. PRLR is required for the signaling and proliferation of prolactin. Prolactin receptors have been localized in a number of peripheral tissues, including tissues involved in reproduction. It is also expressed both in the stromal and epithelial compartment of the mammary gland. Within the immune system, multiple isoforms of the prolactin receptor serve to mediate the effects of its ligand prolactin. These isoforms are structurally and functionally distinct, causing significant differences in ligand affinities, kinetics of transduction and the transduction proteins activated. Differential activation of these pathways may contribute to the pleiotropism of prolactin action in tissues of the immune system. Prolactin receptor is required for normal maternal glucose homeostasis during pregnancy.
Source :
NSO Cells
Purity :
90% by SDS Page and analyzed by silver stain.
UniProt ID :
P16471
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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