This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Plasminogen Activator, Urokinase
catalog :
PLAU-2467H
product information
Cat :
PLAU-2467H
Product Name :
Recombinant Human Plasminogen Activator, Urokinase
Brand :
Creative Biomart
gene symbal :
PLAU
gene name :
plasminogen activator, urokinase
Synonyms :
PLAU; PLAU plasminogen activator, urokinase; ATF; UPA; URK; u-PA urokinase-type plasminogen activator; OTTHUMP00000019849; OTTHUMP00000019850; OTTHUMP00000019851; U-plasminogen activator; plasminogen activator, urinary.
Product Overview :
Recombinant Human plasminogen activator, urokinase was expressed inInsect Cells.MW=18.5 KDa.
Description :
Recombinant Human plasminogen activator, urokinase was expressed inInsect Cells.MW=18.5 KDa.Urokinase-type plasminogen activator is an enzyme that in humans is encoded by the PLAU gene. This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer disease and also with decreased affinity for fibrin-binding. The protein encoded by this gene converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. This gene"s proprotein is cleaved at a Lys-Ile bond by plasmin to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor.
Source :
Insect Cells
Form :
Frozen liquid.
Concentration :
1.0 mg/ml.
UniProt ID :
P00749
company information
Creative BioMart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
headquarters: USA
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.

Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.