This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human PIK3CG, GST-tagged
catalog :
PIK3CG-55H
product information
Cat :
PIK3CG-55H
Product Name :
Recombinant Human PIK3CG, GST-tagged
Brand :
Creative Biomart
gene symbal :
PIK3CG
gene name :
phosphoinositide-3-kinase, catalytic, gamma polypeptide
Synonyms :
PIK3CG; phosphoinositide-3-kinase, catalytic, gamma polypeptide; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; p110gamma; p120-PI3K; PI3K-gamma; p110-gamma; PI3-kinase subunit gamma; ptdIns-3-kinase subunit gamma; 1-phosp
Product Overview :
The Recombinant Human phosphoinositide-3-kinase, catalytic, gamma polypeptide produced inSf9 insect cellsis a catalytically inactive mutant of PI3Kγ with a D946A mutation in the ATP binding site. This recombinant catalytically inactive protein can be used as a negative control in any kind of PI3Kγ kinase activity studies. Recombinant full length PI3KγDA mutant (126.3 kDa without Tag) carries a N-terminal GST-Tag which facilitates the protein's application in typical GST pull-down assays.
Description :
The Recombinant Human phosphoinositide-3-kinase, catalytic, gamma polypeptide produced inSf9 insect cellsis a catalytically inactive mutant of PI3Kγ with a D946A mutation in the ATP binding site. This recombinant catalytically inactive protein can be used as a negative control in any kind of PI3Kγ kinase activity studies. Recombinant full length PI3KγDA mutant (126.3 kDa without Tag) carries a N-terminal GST-Tag which facilitates the protein's application in typical GST pull-down assays.This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.
Source :
Sf9 insect cells
Purity :
Greater than 95.0% as determined by SDS Page.
Storage :
PI3Kb although stable at 14 C for 1 week, should be stored desiccated below -18 C . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
UniProt ID :
P48736
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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