This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human PIK3CD, GST-tagged
catalog :
PIK3CD-52H
product information
Cat :
PIK3CD-52H
Product Name :
Recombinant Human PIK3CD, GST-tagged
Brand :
Creative Biomart
gene symbal :
PIK3CD
gene name :
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Synonyms :
PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; APDS; PI3K; IMD14; p110D; P110DELTA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3Kdelta; phosphoinositide-3-kinase C; PI3-kinase p110 subunit delta; ptdIns-3-kinase subunit p110-delta; phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform;
Product Overview :
Recombinant Human PIK3CD produced inSf9carries a GST-Tag which facilitates the protein's application in typical GST pull-down assays and the heterodimer was purified by affinity chromatography. The molecular weight for p110δ chain is 120.2 kDa (without Tag) and the p85α chain 83.5 kDa.
Description :
Recombinant Human PIK3CD produced inSf9carries a GST-Tag which facilitates the protein's application in typical GST pull-down assays and the heterodimer was purified by affinity chromatography. The molecular weight for p110δ chain is 120.2 kDa (without Tag) and the p85α chain 83.5 kDa.The class IA PI3Kδ is expressed in endothelial and in white blood cells. Recently it was shown that the inactivation of PI3Kδ in bone marrow mast cells (BBMCs) leads to defective stem cell factor-mediated proliferation, adhesion and migration of these cells, and to impaired allergen-IgEinduced degranulation and cytokine release. In neutrophils a role for PI3Kδ in TNFa-induced signaling was demonstrated by a reduction in Aktphosphorylation and PDK1 activity upon treatment with the d-specific inhibitor IC87114.
Source :
Sf9 insect cells
Purity :
Greater than 95.0% as determined by SDS Page.
Storage :
PI3Kb although stable at 14°C for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
UniProt ID :
O00329
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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