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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Mature PCSK9 protein, His-tagged
catalog :
PCSK9-643H
product information
Cat :
PCSK9-643H
Product Name :
Recombinant Human Mature PCSK9 protein, His-tagged
Brand :
Creative Biomart
gene symbal :
PCSK9
gene name :
proprotein convertase subtilisin/kexin type 9
Synonyms :
PCSK9; proprotein convertase subtilisin/kexin type 9; FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3; subtilisin/kexin-like protease PC9; neural apoptosis regulated convertase 1; convertase subtilisin/kexin type 9 preproprotein;
Product Overview :
Recombinant Human PCSK9(Met 1-Gln 692) fussed with His tag at C-terminal was expressed in Wheat Germ.
Description :
Recombinant Human PCSK9(Met 1-Gln 692) fussed with His tag at C-terminal was expressed in Wheat Germ.PCSK9 is a circulating glycosylated serine protease expressed primarily in kidney, liver, cerebellum, and small intestine. In order for secretion to occur, PCSK9 cleaves its own prodomain, which remains associated and largely inhibits further proteolytic activity. The major function of PCSK9 appears to be regulation of circulating cholesterol levels through its binding of the LDL receptor, resulting in degradation of the LDLR. siRNA inhibition of PCSK9 expression lowers plasma PCSK9, apoB, and LDL cholesterol. PCSK9 may also be involved in Alzheimer s disease due to its requirement for degradation of BACE1.
Source :
Human Cells
Form :
Lyophilized from a 0.2um filtered solution of PBS, pH 7.4, containing 8% trehalose, 8% mannitol.
Purity :
97% (SDS-PAGE)
Storage :
Short Term Storage: -80 C
UniProt ID :
Q8NBP7
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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