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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human NGFR, 209aa, Fc Chimera
catalog :
NGFR-452H
product information
Cat :
NGFR-452H
Product Name :
Recombinant Human NGFR, 209aa, Fc Chimera
Brand :
Creative Biomart
gene symbal :
NGFR
gene name :
nerve growth factor receptor
Synonyms :
NGFR; nerve growth factor receptor; p75; LNGFR; p75NTR; RNNGFRR; Tnfrsf16; tumor necrosis factor receptor superfamily member 16; p75 ICD; gp80-LNGFR; NGF receptor; nerve growth factor receptor, fast; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16);
Product Overview :
Recombinant human Nerve growth factor receptor was expressed in modifiedhuman 293 cells. It was fused to the Fc region of human IgG1 (aa 93-330).
Description :
Recombinant human Nerve growth factor receptor was expressed in modifiedhuman 293 cells. It was fused to the Fc region of human IgG1 (aa 93-330).Nerve growth factor receptor (NGFR; NGFR) is a low affinity NGF receptor. NGF R binds with equal affinity all neurotrophins including NGF beta, brain derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) and neurotrophin-5 (NT4/5). The association of NGFR with the other NGF receptors such as TrkA, B and C results in higher affinity ligand binding. Ligand binding to the NGF R can promote either survival or apoptosis of neurons. The effects of neurotrophins exerted through NGF R include conditions such as pain, depression, obesity, nerve regeneration disorders, learning and memory. Additionally, NGFR may play a role in neuronal death that occurs in disorders of the CNS such as Alzheimer's disease.
Source :
human 293 cells
Purity :
95%, as determined by SDS-PAGE and visualized by silver stain.
Storage :
Lyophilized products should be stored at 2 to 8 C. Following reconstitution short-term storage at 4 C is recommended, and longer-term storage of aliquots at -18 to -20 C.
UniProt ID :
P08138
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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