This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human MMP14, Hemopexin Domain, His-tagged
catalog :
MMP14-812H
product information
Cat :
MMP14-812H
Product Name :
Recombinant Human MMP14, Hemopexin Domain, His-tagged
Brand :
Creative Biomart
gene symbal :
MMP14
gene name :
matrix metallopeptidase 14 (membrane-inserted)
Synonyms :
MMP14; matrix metallopeptidase 14 (membrane-inserted); MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1; matrix metalloproteinase-14; membrane type 1 metalloprotease; membrane-type-1 matrix metalloproteinase;
Product Overview :
Recombinant human MT1-MMP hemopexin domain is produced as a periplasmic protein in E. coli.The protein consists of MT1-MMP amino acid residues G292PNIC . CPSGG489 followed by the His-tag VTHHHHHH. The calculated Mr of the recombinant protein is 24 238 Da.
Description :
Recombinant human MT1-MMP hemopexin domain is produced as a periplasmic protein in E. coli.The protein consists of MT1-MMP amino acid residues G292PNIC . CPSGG489 followed by the His-tag VTHHHHHH. The calculated Mr of the recombinant protein is 24 238 Da.Matrix metalloproteinases (MMPs) are Zn2+- and Ca2+-dependent endopeptidases which function in the turnover of extracellular matrix components. Presently fifteen secreted MMPs and six membranetype MMPs are known to be expressed in humans. MT1-MMP consists of 559 amino acid residues with a calculated Mr of 63 516 Da. The following domains and sequence regions are distinguished in MT1-MMP: Prodomain (Ser1 - Arg88), catalytic domain (Tyr89 - Gly261), junction between catalytic domain and hemopexin domain (Gly262 - Gly292), hemopexin-like domain (Pro293 - Cys485) and C-terminal sequence (Pro486 - Val559) with transmembrane segment. A soluble form of MT1-MMP without transmembrane segment has been found in culture medium of a breast carcinoma cell line.
Source :
E coli
Form :
The protein is solubilized in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM CaCl2.
Purity :
MT1-MMP hemopexin domain represents more than 95 % of total protein in the preparation.
UniProt ID :
P50281
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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