This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Leptin
catalog :
LEP-3626H
product information
Cat :
LEP-3626H
Product Name :
Recombinant Human Leptin
Brand :
Creative Biomart
gene symbal :
LEP
gene name :
leptin
Synonyms :
LEP; leptin; obesity factor; OB; obese
Product Overview :
Recombinant Human Leptin produced in E. coli is a single, non-glycosylated, polypeptide chain containing 146 amino acids and having a molecular mass of 15 kDa.
Description :
Recombinant Human Leptin produced in E. coli is a single, non-glycosylated, polypeptide chain containing 146 amino acids and having a molecular mass of 15 kDa.Leptin encoded by obese gene is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signalling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin deficient mice are less active and with lower body temperature than normal animals. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin consists of 167 amino acid residue including a 21 residue signal sequence and 146 residue mature protein sequence.
Form :
The protein was lyophilized from a concentrated (1mg/ml) solution in 20mM PBS, pH 7.4.
Purity :
Greater than 95% as determined by (a) Analysis by RP-HPLC; (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
Storage :
Lyophilized rHuLeptin although stable at room temperature for 3 weeks, should be stored desiccated below -18 C. Upon reconstitution rHuLeptin should be stored at 4 C between 2-7 days and for future use below -18 C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
UniProt ID :
P41159
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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