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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human HIF1A, 576-785 aa, His-tagged
catalog :
HIF1A-2773H
product information
Cat :
HIF1A-2773H
Product Name :
Recombinant Human HIF1A, 576-785 aa, His-tagged
Brand :
Creative Biomart
gene symbal :
HIF1A
gene name :
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Synonyms :
HIF1A; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1-alpha; bHLHe78; HIF 1alpha; HIF1; MOP1; PASD8; HIF-1-alpha; member of PAS protein 1; ARNT interacting protein; ARNT-interacting protein; member of PAS superfamily 1; PAS domain-containing protein 8; basic-helix-loop-helix-PAS protein MOP1; class E basic helix-loop-helix protein 78; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); HIF-1alpha; HIF1-ALPHA
Product Overview :
Recombinant human HIF1A(576-785) protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 25.1 kDa (231aa).
Description :
Recombinant human HIF1A(576-785) protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 25.1 kDa (231aa).HIF1A, identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. This protein is a heterodimer composed of HIF-1beta subunit and one of three subunits(HIF-1A, HIF-2A or HIF-3A). The activation of HIF1A is closely associated with a variety of tumors and oncogenic pathways. HIF1A consists of DNA binding domain(DBD domain), Dimerization domain and C-terminla regulatiory domains, including two transactivation domains(TAD), an oxygen-dependent degradation(ODD) domain, and inhibitory domains.
Source :
Ecoli
Form :
Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 1mM DTT, 10% glycerol.
Purity :
85% by SDS - PAGE.
Concentration :
1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids :
MGSSHHHHHH SSGLVPRGSH MSFDQLSPLE SSSASPESAS PQSTVTVFQQ TQI QEPTANA TTTTATTDEL KTVTKDRMED IKILIASPSP THIHKETTSA TSSPYRDTQS RT A SPNRAGK GVIEQTEKSH PRSPNVLSVA LSQRTTVPEE ELNPKILALQ NA QRK RKMEH DGSLFQAVGI GTLLQQPDDH AATTSLSWKR VKGCKSSEQN GME QKTIILI PSDLACRLLG Q.
Storage :
Can be stored at +4 C short term (1-2 weeks). For long term storage, aliquot and store at -20 C or -70 C. Avoid repeated freezing and thawing cycles.
UniProt ID :
Q16665
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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