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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Fibroblast Growth Factor Receptor 2, Fc Chimera
catalog :
FGFR2-595H
product information
Cat :
FGFR2-595H
Product Name :
Recombinant Human Fibroblast Growth Factor Receptor 2, Fc Chimera
Brand :
Creative Biomart
gene symbal :
FGFR2
gene name :
fibroblast growth factor receptor 2
Synonyms :
FGFR2; BEK; JWS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; Crouzon syndrome; Pfeiffer syndrome; fibroblast growth factor receptor 2; OTTHUMP00000020623; Keratinocyte growth factor receptor; OTTHUMP00000020624; OTTHUMP00000020625; OTTHUMP00000020626; OTTHUMP00000020627; OTTHUMP00000020628; OTTHUMP00000020629; OTTHUMP00000020630; OTTHUMP00000020631; bacteria-expressed kinase; OTTHUMP00000020632; FGFR-2; BEK fibroblast growth factor receptor; FGF receptor; EC 2.7.10.1; hydroxyaryl-protein kinase; protein tyrosine kinase, receptor like 14; soluble FGFR4 variant 4; craniofacial dysostosis 1; Jackson-Weiss syndrome; KSAM; CD332 antigen; FLJ98662; EC 2.7.10; OTTHUMP00000020621
Product Overview :
Recombinant human soluble FGFR-2á (IIIc) was fused via a Xa cleavage site with the Fc part of human IgG1. Human recombinant soluble FGFR-2á (IIIc) is a disulfide-linked heterodimeric protein. The reduced form of human FGF -R2á (IIIc)/Fc is a monomer with a calculated molecular mass of approximately 66 kDa. As a result of glycosylation, the recombinant protein has a mass of 95-100 kDa. It is produced in E.coli .
Description :
Recombinant human soluble FGFR-2á (IIIc) was fused via a Xa cleavage site with the Fc part of human IgG1. Human recombinant soluble FGFR-2á (IIIc) is a disulfide-linked heterodimeric protein. The reduced form of human FGF -R2á (IIIc)/Fc is a monomer with a calculated molecular mass of approximately 66 kDa. As a result of glycosylation, the recombinant protein has a mass of 95-100 kDa. It is produced in E.coli .Fibroblast Growth Factors (FGFs) comprise a family of at least eighteen structurally realted proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family if type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1to -4 are known. Multiple forms of FGFR-1 to -3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGFR-1 and -2 results in receptors containing all three Ig domains, referred to as the á isoform, or only IgII and IgIII, referred to as the isoform. Only the á isoform has been identified for FGFR-3 and FGFR-4.
Source :
Ecoli
Purity :
90%, by SDS-PAGE and visualised by silver stain.
UniProt ID :
P21802
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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