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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Flap Structure-Specific Endonuclease 1
catalog :
FEN1-488H
product information
Cat :
FEN1-488H
Product Name :
Recombinant Human Flap Structure-Specific Endonuclease 1
Brand :
Creative Biomart
gene symbal :
FEN1
gene name :
flap structure-specific endonuclease 1
Synonyms :
FEN1; flap structure-specific endonuclease 1; RAD2; flap endonuclease 1; DNase IV; FEN 1; maturation factor 1; MF1; maturation factor-1; FEN-1
Product Overview :
Recombinant human FEN-1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Description :
Recombinant human FEN-1 protein was expressed in E.coli and purified by using conventional chromatography techniques.FEN-1, also known as Flap structure-specific endonuclease 1, removes 5" overhanging flaps in DNA repair and processes the 5" ends of Okazaki fragments in lagging strand DNA synthesis. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication.
Form :
Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT 10% glycerol
Purity :
90% by SDS - PAGE
Concentration :
1 mg/ml (determined by Bradford assay)
Sequences Of Amino Acids :
MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LQQAQAAGAE QEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALVKAG KVYAAATEDM DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RILQELGLNQ EQFVDLCILL GSDYCESIRG IGPKRAVDLI QKHKSIEEIV RRLDPNKYPV PENWLHKEAH QLFLEPEVLD PESVELKWSE PNEEELIKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP KGSTKKKAKT GAAGKFKRGK
Storage :
Can be stored at +4 C short term (1-2 weeks). For long term storage, aliquot and store at -20 C or -70 C. Avoid repeated freezing and thawing cycles.
UniProt ID :
P39748
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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