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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human CES1, His-tagged
catalog :
CES1-900H
product information
Cat :
CES1-900H
Product Name :
Recombinant Human CES1, His-tagged
Brand :
Creative Biomart
gene symbal :
CES1
gene name :
carboxylesterase 1
Synonyms :
CES1; carboxylesterase 1; CEH; REH; TGH; ACAT; CE-1; CES2; HMSE; SES1; HMSE1; PCE-1; hCE-1; liver carboxylesterase 1; egasyn; serine esterase 1; retinyl ester hydrolase; cocaine carboxylesterase; triacylglycerol hydrolase; carboxylesterase 2 (liver); brain carboxylesterase hBr1; cholesteryl ester hydrolase; monocyte/macrophage serine esterase; methylumbelliferyl-acetate deacetylase 1; acyl coenzyme A:cholesterol acyltransferase; acyl-coenzyme A:cholesterol acyltransferase; human monocyte/macrophage serine esterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1);
Product Overview :
Recombinant Human Carboxylesterase 1/CES1 produced by mammalian cells expression system.Target protein is expressed with sequence (Gly18-Glu563) of Human CES1 fused with a polyhistidine tag at the C-terminus.
Description :
Recombinant Human Carboxylesterase 1/CES1 produced by mammalian cells expression system.Target protein is expressed with sequence (Gly18-Glu563) of Human CES1 fused with a polyhistidine tag at the C-terminus.Carboxylesterase 1 is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds. These enzymes have broad substrate specificity ranging from small molecule esters such as phenylester to long chain fatty acid esters and thioesters. They are major determinants of the pharmacokinetic behavior of most therapeutic agents containing an ester or amide bond. CES1 shares the serine hydrolase fold observed in other esterases. CES1 hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. CES1 participates in detoxification of drugs such as cocaine and heroin in serum and liver. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds.
Source :
Mammalian Cells
Purity :
Greater than 95% as determined by SEC-HPLC. Greater than 95% as determined by reducing SDS-PAGE.
Storage :
Recombinant Carboxylesterase 1/CES1 should be stored desiccated below -18 C.
UniProt ID :
P23141
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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