This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Cyclin-dependent Kinase Inhibitor 1A (p21, Cip1)
catalog :
CDKN1A-169H
product information
Cat :
CDKN1A-169H
Product Name :
Recombinant Human Cyclin-dependent Kinase Inhibitor 1A (p21, Cip1)
Brand :
Creative Biomart
gene symbal :
CDKN1A
gene name :
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Synonyms :
CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1); P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1; cyclin-dependent kinase inhibitor 1; DNA synthesis inhibitor; CDK-interacting protein 1; CDK-interaction protein 1; wild-type p53-activated fragment 1; melanoma differentiation associated protein 6;
Product Overview :
Recombinant Human p21WAF1 protein expressed in E.coli encodes full length amino acids and has a molecular mass of 47 kDa.
Description :
Recombinant Human p21WAF1 protein expressed in E.coli encodes full length amino acids and has a molecular mass of 47 kDa.p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. Meanwhile, the p21WAF1 protein also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process. Evidently, inactivation of p53 disrupts the p53-dependent expression of p21WAF1. p21WAF1is a tumor suppressor involved in the pathogenesis of a variety of malignancies.
Source :
Recombinant full length human p21WAF1 protein expressed inEcoli
UniProt ID :
P38936
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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