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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Complement Component 2, Fc Chimera
catalog :
C2-599H
product information
Cat :
C2-599H
Product Name :
Recombinant Human Complement Component 2, Fc Chimera
Brand :
Creative Biomart
gene symbal :
C2
gene name :
complement component 2
Synonyms :
C2; complement component 2; CO2; ARMD14; complement C2; C3/C5 convertase; complement component C2;
Product Overview :
Recombinant Human complement component 2 was produced inHuman Cells (HEK293), and fused with C-terminal his-tagged Fc region of human IgG1 at the C-terminus.
Description :
Recombinant Human complement component 2 was produced inHuman Cells (HEK293), and fused with C-terminal his-tagged Fc region of human IgG1 at the C-terminus.L1 cell adhesion molecule (L1CAM), also designated as CD171, is a transmembrane cell adhesion molecule belonging to the immunoglobulin superfamily, and has been implicated in a variety of processes integral to the development of the nervous system, including neuronal migration, neurite outgrowth, and axon fasciculation. It is primarily expressed on projection axons of the central nervous system and peripheral nervous system, as well as on a few nonneuronal cell types, such as Schwann cells and lymphocytes. The 1257 amino acid (aa) residue precursor protein contains an extracellular domain consisting of six Ig-like C2-type domains and five fibronectin-type III domains and highly conserved transmembrane and cytoplasmic domains. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan and intergrins, and it has been revealed that the RGD motif in the sixth Ig domain of L1CAM is a binding site for integrins, thus important for nuclear signaling.Disruption of L1CAM function causes three X-linked neurological syndromes, i.e. hydrocephalus, MASA syndrome (mental retardation, aphasia, shuffling gait and adducted thumbs) and spastic paraplegia syndrome. In addition, L1CAM is also overexpressed in a variety of human carcinomas and is associated with bad prognosis.
Source :
Human Cells (HEK293)
Purity :
95%, as determined by SDS-PAGE.
Storage :
Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted and be used as soon as possible. Avoid repeated freeze-thaw cycles.
UniProt ID :
P06681
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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