This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Complement Component 2, His-tagged
catalog :
C2-598H
product information
Cat :
C2-598H
Product Name :
Recombinant Human Complement Component 2, His-tagged
Brand :
Creative Biomart
gene symbal :
C2
gene name :
complement component 2
Synonyms :
C2; complement component 2; CO2; ARMD14; complement C2; C3/C5 convertase; complement component C2;
Product Overview :
Recombinant Human complement component 2 (C2) was produced inHuman Cells (HEK293)and fused with a C-terminal his tag.
Description :
Recombinant Human complement component 2 (C2) was produced inHuman Cells (HEK293)and fused with a C-terminal his tag.Complement component C2 is part of the classical complement pathway which plays a major role in innate immunity against infection. C2 is a glycoprotein synthesized in liver hepatocytes and several other cell types in extrahepatic tissues. This pathway is triggered by a multimolecular complex C1, and subsequently the single-chain form of C2 is cleaved into two chains referred to C2a and C2b by activated C1. C2a containing a serine protease domain combines with complement component C4b to form the C3 convertase C4b2a which is responsible for C3 activation, and leads to the stimulation of adaptive immune responses via Lectin pathway. Deficiency of C2 (C2D) is the most common genetic deficiency of the complement system, and two types of C2D have been recognized in the context of specific MHC haplotypes. C2D in human is reported to increase susceptibility to infection, and is associated with certain autoimmune diseases, such as rheumatological disorders.
Source :
Human Cells (HEK293)
Purity :
97%, as determined by SDS-PAGE and SEC-HPLC Analysis.
Storage :
Store at –70 Avoid repeated freeze-thaw cycles.
UniProt ID :
P06681
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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