This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human APEX Nuclease 1
catalog :
APEX1-593H
product information
Cat :
APEX1-593H
Product Name :
Recombinant Human APEX Nuclease 1
Brand :
Creative Biomart
gene symbal :
APEX1
gene name :
APEX nuclease (multifunctional DNA repair enzyme) 1
Synonyms :
APEX1; APEX nuclease (multifunctional DNA repair enzyme) 1; APE; APX; APE1; APEN; APEX; HAP1; REF1
Product Overview :
Recombinant human APEX1 protein produced inE. coli,36kDa.
Description :
Recombinant human APEX1 protein produced inE. coli,36kDa.Apurinic/apyrimidinic (AP) sites (also called abasic sites ) occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication. All cells, from simple prokaryotes to humans, have evolved systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5" to the AP site, thereby initiating a process known as base excision repair (BER). The APEX gene (alternatively named APE1, HAP1, APEN) encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Source :
E coli
Purity :
≥95% (SDS-PAGE).
Concentration :
1 mg/ml.
Storage :
Enzyme is stable for ~2 weeks at -20 C. After opening, prepare aliquots and store at -80 C. Avoid freeze/thaw cycles.
UniProt ID :
P27695
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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