This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Activin A Receptor Type II-like 1, GST-tagged, Active
catalog :
ACVRL1-238H
product information
Cat :
ACVRL1-238H
Product Name :
Recombinant Human Activin A Receptor Type II-like 1, GST-tagged, Active
Brand :
Creative Biomart
gene symbal :
ACVRL1
gene name :
activin A receptor type II-like 1
Synonyms :
ACVRL1; activin A receptor type II-like 1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1; serine/threonine-protein kinase receptor R3; TGF-B superfamily receptor type I; activin A receptor, type II-like kinase 1;
Product Overview :
Recombinant human ALK1 (144-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=64 kDa.
Description :
Recombinant human ALK1 (144-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=64 kDa.ALK1 is a serine/threonine-protein kinase receptor R3 precursor that mediates signal by TGFβ superfamily. ALK1 functions as a TGFβ type I receptor in endothelial cells and is responsible for human hereditary hemorrhagic telangiectasia (HHT) type II. Distinct Smad proteins (i.e., Smad2/Smad3 and Smad1/Smad5) show interaction with ALK1 and mediate TGFβ signaling. Northern blot and RT-PCR analysis show that ALK1 specifically induces expression of Smad6, Smad7, Id1, Id2, endoglin, STAT1, and interleukin 1 receptor in endothelial cells. ALK1 expression in inflammatory myofibroblastic tumor of the urinary bladder have also has been reported.
Source :
Sf9 insect cells using baculovirus
UniProt ID :
P37023
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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