protein

Recombinant Human Vascular Endothelial Growth Factor 165

VEGFA-50H

Recombinant Human Vascular Endothelial Growth Factor 165

Creative Biomart

VEGFA

vascular endothelial growth factor A

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor;

Recombinant Human Vascular Endothelial Growth Factor produced inCHOcells is a double, glycosylated, polypeptide chain containing 165 amino acids and migrates as 42 kDa in SDS-PAGE under non-reducing conditions. The VEGF is purified by proprietary chromatographic techniques.

Recombinant Human Vascular Endothelial Growth Factor produced inCHOcells is a double, glycosylated, polypeptide chain containing 165 amino acids and migrates as 42 kDa in SDS-PAGE under non-reducing conditions. The VEGF is purified by proprietary chromatographic techniques.Vascular endothelial growth factor is an important signaling protein involved in both vasculogenesis and angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types. VEGF mediates increased vascular permeability, induces angiogenesis, vasculogenesis and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy.

Chinese Hamster Ovarian Cells

Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Lyophilized Vascular Endothelial Growth Factor although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution VEGF should be stored at 4℃between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

P15692