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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Unc-5 Homolog A (C. Elegans), Fc Chimera
catalog :
UNC5A-2437H
product information
Cat :
UNC5A-2437H
Product Name :
Recombinant Human Unc-5 Homolog A (C. Elegans), Fc Chimera
Brand :
Creative Biomart
gene symbal :
UNC5A
gene name :
unc-5 homolog A (C. elegans)
Synonyms :
UNC5H1
Product Overview :
Recombinant Humanunc-5 homolog A (C. elegans) produced inCHO cells.The extracellular domain of UNC5A (UNC5H1) (aa 26-306) is fused to the Fc portion of human IgG1. MW=80kDa.
Description :
Recombinant Humanunc-5 homolog A (C. elegans) produced inCHO cells.The extracellular domain of UNC5A (UNC5H1) (aa 26-306) is fused to the Fc portion of human IgG1. MW=80kDa.The receptors of the UNC family (for uncoordinated) include UNC-5 of C. elegans and its four vertebrate homologs, UNC5A, B, C and D (previously called UNC5H1-4). The UNC5 family binds to the netrin family of ligands and mediates axon repulsion effect of netrin, either alone or by binding to the DCC (another netrin receptor). These receptors are type I transmembrane proteins of roughly 110-120kDa composed of two extracellular Ig-like domains, two thrombospondin type I domains, and intracellular sequence with a ZU5 domain and a death domain. UNC5B is a direct target gene for p53 that mediates p53-dependent apoptosis, and is also a dependence receptor that regulates apoptosis either positively or negatively depending on its binding with netrin-1.
Source :
CHO cells
Purity :
≥95% (SDS-PAGE).
Concentration :
1mg/ml after reconstitution.
UniProt ID :
Q6ZN44
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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