This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human TNFRSF8, Fc-tagged
catalog :
TNFRSF8-1594H
product information
Cat :
TNFRSF8-1594H
Product Name :
Recombinant Human TNFRSF8, Fc-tagged
Brand :
Creative Biomart
gene symbal :
TNFRSF8
gene name :
Tumor Necrosis Factor Receptor Superfamily, Member 8
Synonyms :
CD 30; CD153 antibodyCD30; CD30 antigen; CD30L receptor; Cytokine receptor CD30; D1S166E; KI 1; Ki-1 antigen; KI1; Lymphocyte activation; antigen CD30; TNFRSF8; Tumor Necrosis Factor Receptor Superfamily Member 8; Tumor Necrosis Factor Receptor Superfamily Member 8; Iratumumab; 640735-09-7; Brentuximab vedotin; 914088-09-8
Product Overview :
Recombinant human CD30 (amino acid residues 1 – 379) encoding the extracellular domain was fused to the carboxy-terminal polyhistidine tagged Fc region of human IgG1 via a polypeptide linker. The chimeric protein was expressed inNSO cells.
Description :
Recombinant human CD30 (amino acid residues 1 – 379) encoding the extracellular domain was fused to the carboxy-terminal polyhistidine tagged Fc region of human IgG1 via a polypeptide linker. The chimeric protein was expressed inNSO cells.CD30/TNFRSF8, a type I transmembrane glycoprotein belonging to the TNF receptor superfamily and tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. It is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. CD30 is associated with anaplastic large cell lymphoma. It is expressed in embryonal carcinoma but not in seminoma and is thus is a useful marker in distinguishing between these germ cell tumors.
Source :
NSO Cells
Purity :
95% by SDS Page and analyzed by silver stain.
UniProt ID :
P28908
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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