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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human TNFRSF14, Fc Chimera
catalog :
TNFRSF14-945H
product information
Cat :
TNFRSF14-945H
Product Name :
Recombinant Human TNFRSF14, Fc Chimera
Brand :
Creative Biomart
gene symbal :
TNFRSF14
gene name :
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Synonyms :
TNFRSF14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); TR2; ATAR; HVEA; HVEM; LIGHTR; CD40-like protein; OTTHUMP00000000866; OTTHUMP00000204095; OTTHUMP00000204096; OTTHUMP00000204097; herpesvirus entry mediator A; herpes virus entry mediator A; tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2
Product Overview :
Recombinant human HVEM-Fc Chimera produced inInsect cellsis a 376 amino acid fusion protein containing an N-terminal domain corresponding to the extracellular region of HVEM and a C-terminal domain corresponding to residues 102 to 330 of human IgG1.
Description :
Recombinant human HVEM-Fc Chimera produced inInsect cellsis a 376 amino acid fusion protein containing an N-terminal domain corresponding to the extracellular region of HVEM and a C-terminal domain corresponding to residues 102 to 330 of human IgG1.HVEM belongs to the TNF Receptor superfamily of transmembrane proteins and plays a role in the activation of T-cells and other lymphocytes. It is expressed in various cells and tissues including spleen, thymus, lung, macrophages, and T-cells. HVEM activation induces a signaling cascade which results in induction of transcription factors NF-kappaB and AP-1. LIGHT (TNFSF14) and TNF-beta (TNFSF1) function as the ligands for HVEM, which can also bind specifically to herpes simplex virus glycoprotein D. Soluble HVEM can act as a receptor decoy resulting in inhibition of the activity of the HVEM ligands, LIGHT and TNF-beta.
Source :
Insect cells
Purity :
98%, by SDS-PAGE and HPLC analysis.
UniProt ID :
Q92956
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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