This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human TNFRSF10B, Fc Chimera
catalog :
TNFRSF10B-460H
product information
Cat :
TNFRSF10B-460H
Product Name :
Recombinant Human TNFRSF10B, Fc Chimera
Brand :
Creative Biomart
gene symbal :
TNFRSF10B
gene name :
tumor necrosis factor receptor superfamily, member 10b
Synonyms :
TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b; DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; tumor necrosis factor receptor superfamily member 10B; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; TNF receptor superfamily member 10b; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer);
Product Overview :
Recombinant Humantumor necrosis factor receptor superfamily, member 10b was fused to the Fc region of human IgG1 (aa 90-330). The chimeric protein was expressed in modifiedhuman 293 cells.
Description :
Recombinant Humantumor necrosis factor receptor superfamily, member 10b was fused to the Fc region of human IgG1 (aa 90-330). The chimeric protein was expressed in modifiedhuman 293 cells.TRAILR2, also known as death receptor 5, TNFRSF10B and TNF-related apoptosis-inducing ligand receptor 2, is a type 1 transmembrane protein that contains a death domain in its cytoplasmic domain. TRAILR2 is a receptor for the cytotoxic ligand TRAIL/TNFSF10. TRAILR2 is widely expressed in adult and fetal tissues. TRAILR2 is produced as an ECD-Fc fusion protein with the aim of enhancing its activity. ECD-Fc fusion proteins have an advantage over soluble receptors because many receptors are only functional in dimeric form. Fusion to the Fc domain of IgG1 induces dimerization due to the ability of the Fc domain to form disulfide bonds. The resulting dimeric receptor ECD-Fc mimics the activated form of the receptor and possess enhanced affinity for its cognate ligand relative to its monomeric form.
Source :
human 293 cells
Purity :
95%, as determined by SDS-PAGE and visualized by silver stain.
Storage :
Lyophilized products should be stored at 2 to 8 C. Following reconstitution short-term storage at 4 C is recommended, and longer-term storage of aliquots at -18 to -20 C.
UniProt ID :
O14763
company information
Creative BioMart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
headquarters: USA
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.

Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.