This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human TNF protein, low endotoxin (HPLC-verified)
catalog :
TNF-511H
product information
Cat :
TNF-511H
Product Name :
Recombinant Human TNF protein, low endotoxin (HPLC-verified)
Brand :
Creative Biomart
gene symbal :
TNF
gene name :
tumor necrosis factor
Synonyms :
TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2;
Product Overview :
Recombinant human TNF alpha protein (rhTNFa) Val77-Leu233 (Accession # ?NP_000585.2 ) was produced in human HEK293 cells.
Description :
Recombinant human TNF alpha protein (rhTNFa) Val77-Leu233 (Accession # ?NP_000585.2 ) was produced in human HEK293 cells.Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer"s disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
Source :
HEK293
Form :
Bulk protein in a 0.22 μm filtered solution of PBS, pH 7.4 and delivered as liquid formulation or lyophilized powder.Normally 5-8%. trehalose and mannitol are added as protectants before lyophilization.
Purity :
>98% as determined by SDS-PAGE. All lots are greater than 95% pure.
Storage :
Store at -20 centigrade in lyophilized state after receipt. For long term storage, upon reconstitution rhTNFa should be aliquot and store at -20 centigrade or -80 centigrade. Avoid repeated freeze-thaw cycles.
UniProt ID :
P01375
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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