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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Tumor Necrosis Factor alpha-1a
catalog :
TNF-24H
product information
Cat :
TNF-24H
Product Name :
Recombinant Human Tumor Necrosis Factor alpha-1a
Brand :
Creative Biomart
gene symbal :
TNF
gene name :
tumor necrosis factor
Synonyms :
TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2;
Product Overview :
Tumor necrosis factor alpha-1a or TNFalpha-1a is a non-glycosylated cytokine produced fromE. coliusing rDNA technology. The protein consists of three identical polypeptide chains of 158 amino acids combined to form a compact, bell-shaped homotrimer. The individual subunits have a relative molecular mass each of 17.484 kDa.
Description :
Tumor necrosis factor alpha-1a or TNFalpha-1a is a non-glycosylated cytokine produced fromE. coliusing rDNA technology. The protein consists of three identical polypeptide chains of 158 amino acids combined to form a compact, bell-shaped homotrimer. The individual subunits have a relative molecular mass each of 17.484 kDa.TNF-alpha is a homotrimer with a subunit molecular mass of 17 kDa and that it plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. Besides inducing hemorrhagic necrosis of tumors, TNF was found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn s disease, and rheumatoid arthritis as well as graft-versus-host disease.
Purity :
95% by SDS-PAGE and SEC-HPLC .
UniProt ID :
P01375
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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