This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Thrombopoietin, His-tagged
catalog :
THPO-98H
product information
Cat :
THPO-98H
Product Name :
Recombinant Human Thrombopoietin, His-tagged
Brand :
Creative Biomart
gene symbal :
THPO
gene name :
thrombopoietin
Synonyms :
THPO; thrombopoietin; ML; TPO; MGDF; MKCSF; MPLLG; THCYT1; MPL ligand; c-mpl ligand; prepro-thrombopoietin; megakaryocyte stimulating factor; megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; myeloproliferative leukemia virus oncogene ligand;
Product Overview :
Recombinant Human Thrombopoietin encoding the human TPO (NP_000451.1) precursor (Met 1- Gly 353) with a N-terminal his tag was expressed inHEK293.
Description :
Recombinant Human Thrombopoietin encoding the human TPO (NP_000451.1) precursor (Met 1- Gly 353) with a N-terminal his tag was expressed inHEK293.Thrombopoietin(TPO) is a a hematopoietic growth factor that is involved in the regulation of platelet production. This cytokine is composed of an amino-terminal erythropoietin-like domain which is the functional domain and a highly glycosylated carboxyl domain that appears to stabilize circulating thrombopoietin. TPO stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. It has been identified that surface c-MPL, the receptor for TPO, binds to the ligand and mediates the action. TPO has multilineage effects in hematopoiesis, not only stimulating megakaryocytopoiesis but also acting in synergy with other cytokines to enhance proliferation and survival of committed erythroid progenitors and primitive hematopoietic stem cells. Accordingly, TPO may contribute, at least in part, to leukemogenesis, and represent powerful tools for related analyses.
Source :
Human Cells (HEK293)
Purity :
95%, as determined by SDS-PAGE.
Storage :
Store it under sterile conditions at -70 C immediately after receipt. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
UniProt ID :
P40225
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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