This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human Thrombopoietin
catalog :
THPO-26H
product information
Cat :
THPO-26H
Product Name :
Recombinant Human Thrombopoietin
Brand :
Creative Biomart
gene symbal :
THPO
gene name :
thrombopoietin
Synonyms :
THPO; thrombopoietin; ML; TPO; MGDF; MKCSF; MPLLG; THCYT1; MPL ligand; c-mpl ligand; prepro-thrombopoietin; megakaryocyte stimulating factor; megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; myeloproliferative leukemia virus oncogene ligand;
Product Overview :
Recombinant human TPO produced inCHO, consisting of a 332 amino acid residue with a predicted molecular mass of approximately 35 kDa, migrates with an apparent molecular mass of 80 10 kDa in SDS-PAGE as a result of glycosylation.
Description :
Recombinant human TPO produced inCHO, consisting of a 332 amino acid residue with a predicted molecular mass of approximately 35 kDa, migrates with an apparent molecular mass of 80 10 kDa in SDS-PAGE as a result of glycosylation.Thrombopoietin (Tpo), the ligand for the receptor encoded by the c-Mpl proto-oncogene, is a key regulator of megakaryocytopoiesis and hrombopoiesis in vitro and in vivo. The cDNAs for Tpo have recently been cloned from canine, murine and human sources. The proteins from these three species are highly conserved, exhibiting from 69-75% sequence identity at the amino acid level. Human Tpo cDNA encodes a 353 amino acid residue protein with a 21 amino acid residue signal peptide that is cleaved to yield the 332 amino acid residue mature protein. Two distinct domains, separated by a pair of arginine residues that may be a proteolytic cleavage site, have been identified in Tpo: the amino terminal region exhibiting sequence homology to erythropoietin and the carboxy terminal region containing multiple potential N-linked glycosylation sites. Recombinant Tpo has now been shown to stimulate the maturation, as well as the proliferation, of megakaryocytes and may have important therapeutic applications for the treatment of various clinical conditions associated with thrombocytopenia.
Purity :
98% by SDS-PAGE and HPLC analyses.
UniProt ID :
P40225
company information
Creative BioMart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
headquarters: USA
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.

Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.