This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human TEK Tyrosine Kinase, Endothelial, GST-tagged, Active
catalog :
TEK-445H
product information
Cat :
TEK-445H
Product Name :
Recombinant Human TEK Tyrosine Kinase, Endothelial, GST-tagged, Active
Brand :
Creative Biomart
gene symbal :
TEK
gene name :
TEK tyrosine kinase, endothelial
Synonyms :
TEK; TEK tyrosine kinase, endothelial; TIE2; VMCM; TIE-2; VMCM1; CD202B; venous malformations, multiple cutaneous and mucosal; Angiopoietin-1 receptor; EC=2.7.10.1; Tunica interna endothelial cell kinase; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; hTIE2; p140 TEK; OTTHUMP00000021167; OTTHUMP00000227067; OTTHUMP00000227068; OTTHUMP00000227069; soluble TIE2 variant 1; soluble TIE2 variant 2
Product Overview :
Recombinant human TIE 2 (771-end) was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 61 kDa.
Description :
Recombinant human TIE 2 (771-end) was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 61 kDa.TIE 2 or TEK is a receptor tyrosine kinase that is expressed principally on vascular endothelium. Disrupting TIE 2 function in mice results in embryonic lethality with defects in embryonic vasculature, suggesting a role in blood vessel maturation and maintenance. Angiopoietin-1 is a secreted growth factor that binds to and activates the TIE 2 receptor tyrosine kinase. SHP2 and GRB2 are recruited to the activated TIE 2 kinase domain and are part of the cellular responses that mediate TIE 2 function. TIE 2 expression is upregulated in the endothelium of vascular hot spots in human breast cancer specimens. However, TIE 2 is also overexpressed in areas of active angiogenesis in normal tissues.
Source :
Sf9 insect cells using baculovirus
UniProt ID :
Q02763
company information
Creative BioMart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
headquarters: USA
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.

Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.