This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human TAK1-TAB1, GST-tagged, Active
catalog :
TAK1-TAB1-440H
product information
Cat :
TAK1-TAB1-440H
Product Name :
Recombinant Human TAK1-TAB1, GST-tagged, Active
Brand :
Creative Biomart
gene symbal :
MAP3K7
gene name :
TGF-beta activated kinase 1/MAP3K7 binding protein 1
Synonyms :
MAP; MAP3K; MAP3K7; mitogen-activated protein kinase 7; TAK1; MEKK7; TGF1a; TGF-beta activated kinase 1; transforming growth factor-beta-activated kinase 1
Product Overview :
Recombinant human proteins TAK1 (1-303) and TAB1 (437-end), linked by a small peptide (DFGGGGG), were expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 74 kDa.
Description :
Recombinant human proteins TAK1 (1-303) and TAB1 (437-end), linked by a small peptide (DFGGGGG), were expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 74 kDa.TAK1 is a serine/threonine protein kinase that mediates signaling by TGFβ and morphogenetic protein (BMP). In response to IL-1, TAK1 forms a kinase complex with TAB1 and this complex is required for the activation of nuclear factor kappa B (NfκB). TAK1 can also activate MAPK8/JNK and MAP2K4/MKK4 and thus play a role in the cell response to environmental stress. Tak1 is essential for thymocyte development and activation and deletion of TAK1 prevents maturation of single-positive thymocytes displaying CD4 or CD8. Thymocytes lacking TAK1 fail to activate NfκB and JNK and are prone to apoptosis upon stimulation.
Source :
Sf9 insect cells using baculovirus
UniProt ID :
O43318Q15750
company information
Creative BioMart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
headquarters: USA
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.

Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.