This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human SOX2
catalog :
SOX2-3629H
product information
Cat :
SOX2-3629H
Product Name :
Recombinant Human SOX2
Brand :
Creative Biomart
gene symbal :
SOX2
gene name :
SRY (sex determining region Y)-box 2
Synonyms :
SOX2; SRY (sex determining region Y)-box 2; ANOP3; MCOPS3; transcription factor SOX-2; transcription factor SOX2; SRY-related HMG-box gene 2;
Product Overview :
The recombinant Human Sox2 is produced as C-terminal poly-arginine fusion protein. Recombinant Human Sox2-polyR produced in E. coli is a single, non-glycosylated, polypeptide chain containing 317 amino acids and having a molecular mass of 34.3 kDa.
Description :
The recombinant Human Sox2 is produced as C-terminal poly-arginine fusion protein. Recombinant Human Sox2-polyR produced in E. coli is a single, non-glycosylated, polypeptide chain containing 317 amino acids and having a molecular mass of 34.3 kDa.Transcription factor Sox2 is a member of sox (sry-related HMG box-containing) gene family. Sox2 functions in diverse important developmental processes such as early embryogenesis, neural differentiation and lens development.Sox2 is critically involved in the signaling pathway for maintaining self-renewal and pluripotency of embryonic stem (ES) cells. Sox2 contains an HMG domain in its N-terminal region that recognizes and bends the same DNA sites as SRY and has a transactivation domain at its C terminus. Sox2 and its closely related genes (Sox1 and Sox3) are classified as subfamily group B genes. Sox2 regulates a number of target genes by binding to respective regulatory regions and it has been shown to work in concert with other transcription factors including Oct4 as well as Nanog to support stem cell potency and self-renewal.
Form :
The protein was lyophilized after extensive dialysis against PBS.
Purity :
Greater than 95% as determined by (a) Analysis by RP-HPLC; (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
Storage :
Lyophilized rHuSox2-polyR although stable at room temperature for 3 weeks, should be stored desiccated below -18 C. Upon reconstitution rHuSox2-polyR should be stored at 4 C between 2-7 days and for future use below -18 C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
UniProt ID :
P48431
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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