This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human SH2 Domain Containing 1A, His-tagged
catalog :
SH2D1A-2861H
product information
Cat :
SH2D1A-2861H
Product Name :
Recombinant Human SH2 Domain Containing 1A, His-tagged
Brand :
Creative Biomart
gene symbal :
SH2D1A
gene name :
SH2D1A SH2 domain containing 1A [ Homo sapiens ]
Synonyms :
SH2D1A; LYP; SAP; XLP; DSHP; EBVS; IMD5; XLPD; MTCP1; FLJ18687; FLJ92177; SAP/SH2D1A; SH2 domain-containing protein 1A; OTTHUMP00000023976; OTTHUMP00000226563; SLAM-associated protein; Duncan disease SH2-protein; T cell signal transduction molecule SAP; SLAM associated protein/SH2 domain protein 1A; signaling lymphocyte activation molecule-associated protein; signaling lymphocytic activation molecule-associated protein
Product Overview :
SH2D1A Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 148 amino acids (1-128 a.a.) and having a molecular mass of 16.3kDa. The SH2D1A is purified by proprietary chromatographic techniques.
Description :
SH2D1A acts as an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. The SH2D1A protein is expressed at a high level in the thymus and the lung, with a lower level of expression in the spleen and the liver. The SH2D1A protein contains an SH2 domain and a short tail. SH2D1A has a key role in the bidirectional stimulation of T and B cells. Defects in the SH2D1A gene cause the X-linked lymphoproliferative disease (XLPD), aka Duncan disease. The XLPD is distinguished by a rare congenital immunodeficiency following an EBV infection (Epstein-Barr virus).
Source :
Human
Form :
The SH2D1A solution (1 mg/ml) contains 20mM Tris-HCl Buffer (pH 7.5), 1mM DTT and 10% Glycerol.
Purity :
Greater than 95.0% as determined by SDS-PAGE.
Storage :
SH2D1A should be stored desiccated below -18 C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
UniProt ID :
O60880
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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