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product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human SELP
catalog :
SELP-1674H
product information
Cat :
SELP-1674H
Product Name :
Recombinant Human SELP
Brand :
Creative Biomart
gene symbal :
SELP
gene name :
selectin P (granule membrane protein 140kDa, antigen CD62)
Synonyms :
SELP; selectin P (granule membrane protein 140kDa, antigen CD62); GRMP, selectin P (granule membrane protein 140kD, antigen CD62); P-selectin; CD62; CD62P; GMP140; PADGEM; PSEL; GMP-140; granule membrane protein 140; granulocyte membrane protein; CD62 antigen-like family member P; platelet alpha-granule membrane protein; leukocyte-endothelial cell adhesion molecule 3; platelet activation dependent granule-external membrane protein; GRMP; LECAM3; FLJ45155
Product Overview :
The extracellular domain of human P-Selectin (amino acid residues 1 - 771) was fused to the Fc region of human IgG1 via a polypeptide linker. Recombinant Human selectin P (granule membrane protein 140kDa, antigen CD62) was inserted into a suitable mammalian expression vector and expressed inNSO cells.
Description :
The extracellular domain of human P-Selectin (amino acid residues 1 - 771) was fused to the Fc region of human IgG1 via a polypeptide linker. Recombinant Human selectin P (granule membrane protein 140kDa, antigen CD62) was inserted into a suitable mammalian expression vector and expressed inNSO cells.Plasma Selectin (P-selectin) is a cell adhesion molecule (CAM) found in granules in endothelial cells (cells lining blood vessels) and activated platelets. P-Selectin is expressed on activated endothelium and platelets where it can bind monocytes, neutrophils, stimulated T cells, and platelets. P-selectin plays an essential role in the initial recruitment of leukocytes (white blood cells) to the site of injury during inflammation. When endothelial cells are activated by molecules such as histamine or thrombin during inflammation, P-selectin moves from an internal cell location to the endothelial cell surface. Thrombin is one trigger which can stimulate endothelial-cell release of P-selectin and recent studies suggest an additional Ca2+-independent pathway involved in release of P-selectin. P-selectin-mediated adhesion is an important factor in the development of early atherosclerotic lesions.
Source :
NSO cells
Purity :
95% by SDS Page and analyzed by silver stain.
Storage :
This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
UniProt ID :
P16109
company information
Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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