This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Human ROCK2, GST-tagged, Active
catalog :
ROCK2-421H
product information
Cat :
ROCK2-421H
Product Name :
Recombinant Human ROCK2, GST-tagged, Active
Brand :
Creative Biomart
gene symbal :
ROCK2
gene name :
Rho-associated, coiled-coil containing protein kinase 2
Synonyms :
ROCK2; Rho-associated, coiled-coil containing protein kinase 2; ROCK-II; rho-associated protein kinase 2; p164 ROCK-2; rho-associated, coiled-coil-containing protein kinase II;
Product Overview :
Recombinant human ROCK2 (5-554) was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=88kDa.
Description :
Recombinant human ROCK2 (5-554) was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=88kDa.ROCK2 is a ubiquitously expressed serine/threonine kinase localized in the nucleus that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. ROCK2 is an immediate downstream target of the small GTPase RhoA. ROCK2 may play a pivotal role in cardiovascular diseases such as vasospastic angina, ischemic stroke, and heart failure. Inhibition of ROCKs by statins or other selective inhibitors leads to the upregulation and activation of endothelial nitric oxide synthase (eNOS) and reduction of vascular inflammation and atherosclerosis.
Source :
Sf9 insect cells using baculovirus
UniProt ID :
O75116
company information

Creative BioMart
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.
We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.
Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.
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