This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Creative BioMart
product type :
protein
product name :
Recombinant Rat Ptpn1, GST-tagged
catalog :
Ptpn1-456R
product information
Cat :
Ptpn1-456R
Product Name :
Recombinant Rat Ptpn1, GST-tagged
Brand :
Creative Biomart
gene symbal :
Ptpn1
gene name :
protein tyrosine phosphatase, non-receptor type 1
Synonyms :
PTPN1; protein tyrosine phosphatase, non-receptor type 1; PTP1B; tyrosine-protein phosphatase non-receptor type 1; protein tyrosine phosphatase 1B; protein-tyrosine phosphatase 1B; protein tyrosine phosphatase, placental
Product Overview :
Recombinant Rat Protein tyrosine phosphatase, Catalytic domain, (a.a. 1-321), with N-terminal GST tag expressed in an E.coli expression system. MW= 63.3 kDa.
Description :
Recombinant Rat Protein tyrosine phosphatase, Catalytic domain, (a.a. 1-321), with N-terminal GST tag expressed in an E.coli expression system. MW= 63.3 kDa.Tyrosine-protein phosphatase non-receptor type 1 is an enzyme that in humans is encoded by the PTPN1 gene. The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.
Source :
EColi
Purity :
95% by SDS-PAGE.
UniProt ID :
P20417
company information
Creative BioMart
NY, USA
contact@creative-biomart.com
http://www.creativebiomart.net
1-516-855-7709
headquarters: USA
Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 3,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.

Also, in order to leverage our core competencies and resources, Creative BioMart has formed a large number of corporate partnerships and academic collaborations for product development and distribution. We welcome potential partners and distributors to explore business relationships with Creative BioMart.